Genomics · Genetic Reports · Precision Wellness
Bone Health
Personalized Genetic Report
Bone Health ProblemsBone Health Nutrients
Accession #: MRW-26-13784A
Report type: Full Report
Report status: FINAL
Specimen and client information
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
What this report covers
Bone Health Problems · Bone Health Nutrients
About this report
This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.
What each result group means
Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.
Your results at a glance
How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 17 results here, 4 came back worth discussing with a clinician and 2 came back in your favour. Bring this document to your appointment.
Worth a conversation with your doctor (4)These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
From your Bone Health report
ABone Cancer
More likely
Higher predisposition than average
PARM1 rs17248137 AA · LRMDA rs17465450 AA · MECOM rs6797464 GG · GPD1L rs4955138 AA · HSPB8 rs12146774 TC · ADAMTS6 rs17206779 TC · DLEU7 rs573666 CC
AHypoparathyroidism
More likely
Higher predisposition than average
ACalcium
Increased need
Higher predisposition than average
CTNNB1 rs389264 CC · RSPO3 rs9482772 CC · AMT rs34240317 IA · CPED1 rs10242100 AA · ARL4C rs12151790 GG · FKBP11 rs3741619 GA · ETS2 rs11088458 AG · HBZ rs10794639 GA
AVitamin K
Increased need
Higher predisposition than average
CDO1 rs6862071 AT · CDO1 rs4122275 GA · SIDT2 rs964184 CC · CTNNA2 rs4852146 TT · CYP4F2 rs2108622 CC · KCNK9 rs4645543 CC
Running above the typical range (1)Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
From your Bone Health report
HGC (Vitamin D)
Higher activity
Above the typical range
GC rs2282679 GT
Running below the typical range (0)Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour (2)Good news. Your genetics look protective or better than average here.
From your Bone Health report
FScoliosis
Less likely
Lower predisposition than 81% of people
DPCD rs11190870 CT · OBSCN rs12029076 GG · CCDC171 rs78223574 AA · FTO rs12149832 GG · TBX1 rs1978060 GG · CREB5 rs160335 GG · ADGRG6 rs9389985 GA · BNC2 rs7028900 CG
FBone Spurs
Less likely
Lower predisposition than 95% of people
CAPRIN2 rs542887566 CC · NPAP1 rs577272962 AA · PIK3R1 rs143106204 CC · PPP1CB rs193167778 CC · PCDH9 rs369611135 TT
In line with most people (10)Nothing unusual. These were tested and came back typical — worth having on record.
From your Bone Health report
·Bone Infection
Typical likelihood
In line with the general population · 65th percentile
·Spinal Canal Narrowing
Typical likelihood
In line with the general population · 60th percentile
IPP rs2356581 AA · DYNC1I1 rs2051706 GG · TRIM32 rs1040851 CC · PDE3A rs7298820 AT · SMAD3 rs28613758 CT · SLITRK6 rs2183749 AC · ELMOD2 rs184579809 TT · HEY1 rs143958409 CC
·Fractures
Typical likelihood
In line with the general population · 37th percentile
MARCO rs115242848 CC · HLA-DQA1 rs2071805 CC · VARS2 rs9262558 CC · SP7 rs144680237 CC · CPED1 rs3779381 AA · ZBTB40 rs34414754 AA · WLS rs2566755 TT · NTNG1 rs76259395 AA
·Osteoporosis
Typical likelihood
In line with the general population · 33th percentile
MARCO rs115242848 CC · COPB1 rs10741657 GG · CPNE1 rs143383 AA · CPED1 rs3779381 AA · ZBTB40 rs34414754 AA · WLS rs2566755 TT · CPED1 rs10242100 AA · FKBP11 rs3741619 GA
·Hyperparathyroidism
Typical likelihood
In line with the general population
FIBIN rs375264315 CC · MRPS31 rs141641942 CC · LRFN5 rs117828799 AG · MED13L rs139671128 GA · RASSF3 rs190001302 TT · SFTPA1 rs146467844 AA · TEX26 rs73165078 AA · HMX3 rs80212821 CC
·Vitamin D
Typical need
In line with the general population
COPB1 rs12794714 AA · COPB1 rs10832289 TT · GC rs2282679 GT · VDR rs2228570 GA · PDE3B rs571484036 AA · GC rs222026 TT · GC rs4588 TG · VDR rs731236 AG
·Phosphate
Typical levels
In line with the general population
NBPF3 rs1697421 TC · IP6K3 rs9469578 CC · C12ORF4 rs2970818 TT · AHI1 rs947583 TT · CSTA rs17265703 AA
·Magnesium
Typical need
In line with the general population
TRPM6 rs11144134 TT · VIPR1 rs11718502 TC · THBS3 rs4072037 TC · PAPSS2 rs791888 GG · RALGDS rs7032317 CT · CDKL2 rs6838240 CT · ALPK1 rs2074379 AG · C8ORF48 rs10888073 CT
·VDR (Vitamin D)
Typical activity
In line with the general population
VDR rs2228570 GA · VDR rs1544410 CT · VDR rs7975232 AA
·CYP2R1 (Vitamin D)
Typical activity
In line with the general population
COPB1 rs10741657 GG · COPB1 rs10766197 AA
Methodology
Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.
Limitations
This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.
Performing laboratory & attestation
| Performing laboratory | Gene by Gene, Ltd. |
| Laboratory address | 1445 North Loop West, Suite 760, Houston, TX 77008 |
| CLIA certification | CLIA #45D1102202 |
| CAP accreditation | CAP #7212851 · accredited through 7 October 2027 |
| Laboratory Director | Feng Zhou, PhD, MB(ASCP) |
| Specimen type | Buccal (cheek) swab — genomic DNA |
| Accession | MRW-26-13784A |
| Date reported | 29 July 2026 |
This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-13784A · © 2026 Marrow Health.