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Genomics · Genetic Reports · Precision Wellness

Hormone Health

Personalized Genetic Report
Thyroid HormonesReproductive HormonesMetabolic HormonesStress HormonesHormone Genes
Sample ClientReport date: 29 July 2026
Genomics · Genetic Reports · Precision Wellness
Marrow Health Laboratories
Marrow
Accession #: MRW-26-6AFD86
Report type: Full Report
Report status: FINAL

Specimen and client information

Client
Sample Client
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
Accession
MRW-26-6AFD86
Panel
Hormone Health
Results scored
46
Need attention
1
Report
Full Report

What this report covers

Thyroid Hormones · Reproductive Hormones · Metabolic Hormones · Stress Hormones · Hormone Genes

About this report

This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.

What each result group means

Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.

Your results at a glance

How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 46 results here, 1 came back worth discussing with a clinician and 0 came back in your favour. Bring this document to your appointment.
Worth a conversation with your doctor  (1)These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
From your Hormone Health report
ATCF7L2 (Blood Sugar/Diet)
Worse genetics
Higher predisposition than average
TCF7L2 rs7903146 CT · TCF7L2 rs12255372 GT
Running above the typical range  (9)Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
From your Hormone Health report
HFSH
Higher levels
Above the typical range
FSHR rs2300441 GA · UBE3A rs4109610 TT · CYP19A1 rs2414095 GG · GAD2 rs8190595 CC · ZNF438 rs187634935 GG · PTER rs116990127 CC · PFKFB3 rs12269260 TT · KLF6 rs183217426 CC
HSHBG
Higher levels
Above the typical range
TNFSF12 rs4227 TT · TP53 rs1042522 CC · TP53 rs1625895 CC · TNFSF12 rs4968200 GG · TNFSF12 rs3803800 GA · SERPINA1 rs28929474 CC · SAT2 rs55784804 GG · SPEM1 rs199795512 TT
HEstradiol (M)
Higher levels
Above the typical range
ESR1 rs728524 AA · ESR1 rs9340799 GA · ESR1 rs2234693 CT · XDH rs559555 TT · GCKR rs1260326 TC · EDA2R rs12850857 G · SRD5A2 rs112881196 CC · FKBP4 rs56196860 CC
HTestosterone
Higher levels
Above the typical range
FKBP4 rs56196860 CC · EDA2R rs141086308 C · TNFSF12 rs727428 TT · PDE7B rs7774640 GG · FAM9A rs5934505 T · TNFSF12 rs12946520 TG · NR2F2 rs8023580 TT · MYPOP rs35318830 TT
HMTNR1B (Diet & Blood Sugar)
Higher activity
Above the typical range
HDIO1 (Thyroid)
Higher activity
Above the typical range
DIO1 rs2235544 CC
HDIO2 (Thyroid)
Higher activity
Above the typical range
DIO2 rs225014 TT
HGHR
Higher activity
Above the typical range
ATP2B2 rs56284847 CC · ATP2B2 rs34892 AA · ATP2B2 rs34884 CC · TATDN2 rs168529 AG · GHRL rs35680 CT · GHRL rs35683 AC · TATDN2 rs1063429 AT · GHRL rs35681 TC
HMC4R (Weight/ Blood Sugar)
Higher activity
Above the typical range
MC4R rs17782313 TT
Running below the typical range  (8)Your genetics point to these sitting lower than average. Same idea — context, not alarm.
From your Hormone Health report
LDHEAS
Lower levels
Below the typical range
BCL2L11 rs6738028 CC · PLEKHH2 rs77533229 GG · ZKSCAN5 rs77356530 GG · CYP3A7 rs80193476 AA · ZKSCAN5 rs10278040 GG · PUDP rs5935876 G · ZKSCAN5 rs150507409 GG · SULT2A1 rs2637125 GG
LLuteinizing Hormone (LH)
Lower levels
Below the typical range
LHB rs139643250 TC · LHB rs3795047 TA · LHB rs3795052 CA
LPregnenolone
Lower levels
Below the typical range
SLCO1B1 rs4149056 TC · SLCO1B1 rs11519274 CT · IL7R rs6873506 CC · IL7R rs10491431 CC · AKR1C3 rs74827952 GG · AKR1C3 rs7078211 AA · CABP5 rs16981893 GG · KIF20B rs7095217 CC
LProlactin
Lower levels
Below the typical range
VTN rs704 GG · CPB2 rs1926447 GG
LGLP-1
Lower levels
Below the typical range
RAPGEF4 rs150495482 CC · GPT rs139849083 CC · ADAP1 rs1568773 AA
LCRHR2 (Stress/HPA Axis)
Lower activity
Below the typical range
CRHR2 rs2267715 AA · CRHR2 rs2190242 AA
LCRHR1 (Stress/HPA Axis)
Lower activity
Below the typical range
ARHGAP27 rs4792887 CC
LFKBP5 (Stress/ HPA Axis)
Lower activity
Below the typical range
FKBP5 rs1360780 CC · TULP1 rs9470080 CC · FKBP5 rs9394314 AG
Working in your favour  (0)Good news. Your genetics look protective or better than average here.
Nothing in this group.
In line with most people  (28)Nothing unusual. These were tested and came back typical — worth having on record.
From your Hormone Health report
·Hashimoto's Disease
Typical likelihood
In line with the general population · 47th percentile
IL6 rs1800795 GG · CTLA4 rs34636506 AA · STAT4 rs11889341 CT · TPO rs11675434 CT · CTLA4 rs231775 AG · CD69 rs2110451 AG · RPS26 rs11611029 CT · NIPSNAP1 rs757024 GC
·Overactive Thyroid
Typical likelihood
In line with the general population · 46th percentile
CTLA4 rs3087243 GG · FCRL3 rs7522061 CT · TSHR rs12101261 CT · CD40 rs1883832 TC · MICB rs2517532 GA · FAM227B rs17477923 TT · PDE10A rs2983514 GG · PDE8B rs2046045 GT
·Underactive Thyroid
Typical likelihood
In line with the general population · 34th percentile
CTLA4 rs3087243 GG · TSHR rs12101261 CT · SH2B3 rs653178 CT · RASGRP1 rs12593201 AA · TPO rs732609 AC · SESN3 rs4409785 TC · CLECL1 rs370475698 IT · ARID5B rs71508903 CT
·Free T4
Typical levels
In line with the general population
AADAT rs7694879 TC · ILRUN rs73405691 AA · H2BC1 rs9356988 AA · DIO2 rs225014 TT · SLCO1B1 rs4149056 TC · RNF144B rs10946313 TC · USP3 rs12907106 GC · NUCKS1 rs951366 TC
·T3 (Triiodothyronine)
Typical levels
In line with the general population
FBLL1 rs590784 AC · SERPINA7 rs12687280 T · EPHB2 rs67142165 CC · RAB38 rs116951285 TT · PRKCE rs10192064 TT · MOV10L1 rs2066773 GG · VPS37B rs76465767 TT · AGPAT2 rs7020640 CC
·T4 (Thyroxine)
Typical levels
In line with the general population
MC4R rs56069042 AA · AADAT rs7694879 TC · SEPHS1 rs72783371 AA · CA8 rs67583169 CC · ILRUN rs73405691 AA · LRRC42 rs12127960 TA · H2BC1 rs9356988 AA · DIO2 rs225014 TT
·TSH
Typical levels
In line with the general population
LRRC6 rs117764941 GG · NFIA rs334725 AA · PDE8B rs2928167 AA · NR3C2 rs11732089 TT · TBX2 rs1157994 GG · FAM227B rs17477923 TT · VEGFA rs1317983 CT · TNP1 rs13020935 GA
·Graves' Disease
Typical likelihood
In line with the general population
TSHR rs179247 AA · UHRF1BP1 rs9469899 AA · TSHR rs28414437 AC · TPO rs11675434 CT · IGLV3-21 rs5751536 GA · TSHR rs2300519 TA · CD40 rs1569723 CA · FCRL3 rs1977710 GA
·Reverse T3 (rT3)
Typical levels
In line with the general population
DIO1 rs11206244 CC
·Free T3 (fT3)
Typical levels
In line with the general population
·Bioavailable Testosterone
Typical levels
In line with the general population
SRD5A2 rs113017476 GG · PPP2R3C rs10137488 TT · KCNIP4 rs7679843 CC · MME rs61762319 AA · ORM1 rs10982156 TT · CYP19A1 rs17703883 TT · ABT1 rs79310511 AA · RORB rs912202 GG
·DHT
Typical levels
In line with the general population
TNFSF12 rs1799941 GG
·Progesterone
Typical levels
In line with the general population
HSD17B12 rs142754737 CC · SESN3 rs139203625 CC · CD34 rs138621610 GG · ARNTL rs77032081 CC · RBFOX1 rs144711998 CC · LYSMD3 rs139441768 TT · ARRDC3 rs140935700 GG · ZKSCAN5 rs34670419 GG
·Insulin
Typical levels
In line with the general population
HDAC7 rs111264094 CC · PPARG rs11712037 CC · PPARG rs1801282 CC · RFC4 rs17300539 GG · FOXO3 rs2802292 GG · IGF1 rs860598 AA · BMP2 rs979012 TT · PPARGC1A rs8192678 TC
·Ghrelin
Typical levels
In line with the general population
ATP2B2 rs56284847 CC · ATP2B2 rs34892 AA · ATP2B2 rs34884 CC · TATDN2 rs168529 AG · GHRL rs35680 CT · GHRL rs35683 AC · TATDN2 rs1063429 AT · GHRL rs35681 TC
·IGF-1
Typical levels
In line with the general population
SSTR5 rs121917877 CC · IGFBP3 rs9282734 TT · ABHD14A-ACY1 rs121912698 CC · MAP1A rs55707100 CC · IGFALS rs34680334 GG · HNF1A rs1800574 CC · EIF3J rs151291132 AA · STARD9 rs202077402 AA
·Leptin
Typical levels
In line with the general population
LEP rs10487505 GG · KLF14 rs972283 GG · KLHL31 rs3799260 TT · SLC38A11 rs6738627 GA · LEP rs791600 GG
·Adiponectin
Typical levels
In line with the general population
ZNF664 rs7978610 GG · IRS1 rs1515110 GT · ARL15 rs6450176 AG · TRIB1 rs2980879 AT · LYPLAL1 rs2061155 TC · PDE3A rs7955516 CA · CITED2 rs668459 TC · ZC3H11B rs3001032 TC
·Growth Hormone
Typical levels
In line with the general population
FOXL3 rs139113181 CC · TMEM106B rs1003433 TT · METTL4 rs116932378 AA · HMSD rs1123485 AA · PUM3 rs117939495 CC · RANBP6 rs12380605 AA · AGMO rs74758223 GA · FAM78B rs10918439 AG
·Cortisol
Typical levels
In line with the general population
CNTNAP5 rs11899245 TC · FKBP5 rs1360780 CC · DGKH rs1170109 GT · PDE10A rs2983496 AG · LDLR rs5927 GA · ZFP42 rs6849009 CC · INHBA rs10244501 CC · TFAP2C rs6069930 GG
·Cushing’s Syndrome
Typical likelihood
In line with the general population
·Addison’s Disease
Typical likelihood
In line with the general population
·HPA Axis
Typical likelihood
In line with the general population
ARHGAP27 rs4792887 CC · CRHR2 rs2267715 AA · NR3C1 rs6196 AA · MAPT rs12938031 GA · FKBP5 rs9394314 AG · NR3C1 rs1866388 GA · NR3C1 rs10052957 AG · IFI27L1 rs11621961 CT
·TPO (Thyroid)
Typical
In line with the general population
TPO rs11675434 CT
·ESR1 (Estrogen)
Typical activity
In line with the general population
·ADIPOQ (Weight/ Blood Sugar)
Typical genetics
In line with the general population
ADIPOQ rs2241766 GT
·LEPR (Weight/Leptin Resistance)
Typical activity
In line with the general population
LEPR rs1137101 AG
·GIPR (Blood Sugar)
Typical activity
In line with the general population
GIPR rs2287019 CC · GIPR rs10423928 TT

Methodology

Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.

Limitations

This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.

Performing laboratory & attestation
Performing laboratoryGene by Gene, Ltd.
Laboratory address1445 North Loop West, Suite 760, Houston, TX 77008
CLIA certificationCLIA #45D1102202
CAP accreditationCAP #7212851 · accredited through 7 October 2027
Laboratory DirectorFeng Zhou, PhD, MB(ASCP)
Specimen typeBuccal (cheek) swab — genomic DNA
AccessionMRW-26-6AFD86
Date reported29 July 2026

This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-6AFD86 · © 2026 Marrow Health.