From your Inflammation & Autoimmunity report
·Ulcerative Colitis
Typical likelihood
In line with the general population · 63th percentile
STAT3 rs744166 AA · HNF4A rs6017342 CC · HLA-DQA2 rs2395185 TG · IL23R rs76418789 GG · IL23R rs11805303 CT · MFSD4B rs3851228 AA · NR5A2 rs2816958 GG · IL19 rs1800872 GG
·Multiple Sclerosis
Typical likelihood
In line with the general population · 60th percentile
EBPL rs9591325 TT · IL2RA rs2104286 TT · RBM17 rs11256593 TT · TYK2 rs34536443 GG · TAPBPL rs12832171 CC · JAK1 rs72922276 GG · RGS1 rs1323292 AA · RTEL1-TNFRSF6B rs6742 CC
·Stomach Inflammation
Typical likelihood
In line with the general population · 42th percentile
MRPL13 rs7826906 GA · CCDC66 rs6445797 GG · MTBP rs10955971 AG · CDC37 rs8112449 AG · TCP10L rs11088226 CC
·Celiac Disease
Typical likelihood
In line with the general population · 42th percentile
HLA-DRB5 rs2395182 TG · HLA-DQA2 rs7454108 TT · HLA-DQA1 rs2187668 CC
·Rheumatoid Arthritis
Typical likelihood
In line with the general population · 40th percentile
HLA-DQA2 rs6457617 TC · CTLA4 rs3087243 GG · ANKRD55 rs7731626 GG · ETS1 rs73013527 CC · RUNX1 rs8133843 AA · LBH rs7579944 CC · PODXL rs11761231 CC · ARID5B rs71508903 CT
·HRH4 (Allergies, Inflammation)
Typical activity
In line with the general population · 39th percentile
IMPACT rs524149 CC · HRH4 rs17797945 CC · HRH4 rs657132 GG · OSBPL1A rs527790 CC
·Inflammation (CRP)
Typical levels
In line with the general population · 36th percentile
CRP rs1205 CC · IL6R rs2228145 CC · FUT2 rs601338 AG · IL19 rs3024505 AG · IL4R rs1805011 AA · IL1RN rs419598 TT · ATG16L1 rs10210302 TT · ATG16L1 rs2241880 GG
·Eczema
Typical likelihood
In line with the general population · 29th percentile
IL6R rs61812598 AA · ADO rs4372325 CC · D2HGDH rs34290285 GG · ARHGAP27 rs9895436 AA · TREH rs10790275 CG · MDM1 rs2227491 TC · FLG rs138726443 GG · LINGO4 rs12123821 CC
·IL-6
Typical levels
In line with the general population · 20th percentile
ATP9A rs73273528 CC · SOX4 rs185628618 GG · TBKBP1 rs72831623 GG · TBKBP1 rs113600793 CC · IL6R rs4537545 TT · AKNA rs10982213 GG · SERPINE2 rs13412535 GA · CASS4 rs1884910 GC
·Type 1 Diabetes
Typical likelihood
In line with the general population · 15th percentile
IL19 rs3024505 AG · ERBB3 rs11171739 CT · RTL1 rs56994090 CT · DEXI rs12708716 GA · IL7R rs11954020 GG · MAPT rs1052553 AA · CLEC2D rs3764021 CT · TYK2 rs34536443 GG
·Lupus
Typical likelihood
In line with the general population · 12th percentile
IRF8 rs11644034 GG · NADSYN1 rs3794060 CC · PRDM1 rs6568431 AA · IKZF1 rs4917014 TT · LYST rs9782955 CC · ZFP36L1 rs4902562 AA · UBE2L3 rs7444 CT · SLU7 rs2431697 TC
·Chronic Lyme
Typical likelihood
In line with the general population
TLR2 rs5743708 GG · HLA-DQA2 rs6910071 GA · DDAH2 rs9267658 CT · HLA-DQA2 rs17208888 GG · TLR1 rs5743618 AA · ABCB1 rs1128503 GG · HLA-DOB rs3817964 TT · C6ORF47 rs4947332 CC
·Sepsis
Typical likelihood
In line with the general population
RIN3 rs149187226 GG · CHRM2 rs142021422 CC · KLHDC10 rs181021474 TT · MAD1L1 rs147296048 AA
·Pulmonary Fibrosis
Typical likelihood
In line with the general population
NCF2 rs17849502 GT · GLS rs13389408 TC · CCDC116 rs5754467 GA · TNFAIP3 rs58721818 CC · METTL27 rs193107685 TT · TNIP1 rs4958880 CC · IDUA rs13101828 AA · ALDH2 rs11066301 GA
·Actinic Keratosis
Typical likelihood
In line with the general population
BNC2 rs12350739 AG · HERC2 rs12916300 TC · FOXP1 rs7638354 TA · SLC45A2 rs16891982 GG
·Meningitis
Typical likelihood
In line with the general population
SGCD rs13358188 AA · SIK3 rs116886525 CC · ISL2 rs188530871 CC · CD28 rs189257688 CC · ITPKB rs17587821 TT · RCN1 rs61878814 TT · CACNA1E rs116306652 GG · RERE rs35608792 AA
·Sarcoidosis
Typical likelihood
In line with the general population
ZNF439 rs76054429 TT · PRRG4 rs143440435 TT · HLA-DMA rs9276935 TT · HLA-DQA2 rs3101944 CC · HLA-DRB1 rs28589559 GG · ZNF578 rs73575927 CT · TNR rs732292 AA · HLA-DRB1 rs9271346 TC
·Rheumatic Fever
Typical likelihood
In line with the general population
·Psoriatic Arthritis
Typical likelihood
In line with the general population
TYK2 rs34536443 GG · MICB rs13191343 TC · IL12B rs4921482 TT · STAT2 rs2020854 TT · IL12B rs62377586 GG · SLC22A5 rs848 CC · NXPE3 rs4683946 GG · CNTN4 rs17194140 TT
·Ankylosing Spondylitis
Typical likelihood
In line with the general population
IL23R rs11209026 GG · ERAP2 rs10045403 AA · NKX2-3 rs11190133 CC · ERAP1 rs30187 CT · CARD9 rs1128905 CC · INAVA rs41299637 TG · ETS2 rs2836883 AG · ERAP2 rs2910686 CT
·Vitiligo
Typical likelihood
In line with the general population
ASIP rs6059655 GG · HLA-A rs60131261 GG · DEF8 rs4268748 TT · IRF4 rs12203592 CC · TICAM1 rs4807000 AA · PTPRC rs16843742 TT · HLA-DQA2 rs9271597 AT · TYR rs1126809 AG
·Alopecia Areata
Typical likelihood
In line with the general population
PPARGC1A rs16873952 AA · NTM rs11600229 AA · CPVL rs505532 TT · ARHGAP42 rs11224294 CT · DISP3 rs3099624 CC · ST8SIA5 rs9952976 AA · CCDC24 rs304303 TG · ST3GAL3 rs4660260 TC
·Systemic Sclerosis
Typical likelihood
In line with the general population
GLS rs13389408 TC · CCDC116 rs5754467 GA · TNFAIP3 rs58721818 CC · TNPO3 rs13238352 CC · PTPN22 rs6679677 CC · TRIM59 rs112846137 GG · BLK rs2736337 TT
·Pemphigus Vulgaris
Typical likelihood
In line with the general population
EPHA5 rs1074532 AA · ANK2 rs362492 CC · UCN3 rs9423602 GG · SOX9 rs17246777 CC · CDH4 rs6093035 AA · ANKFN1 rs9899680 TT · PADI6 rs10888028 TT · STK32A rs62377684 TT
·Behcet’s Disease
Typical likelihood
In line with the general population
IL12A rs17810546 AA · CCR3 rs2087726 AA · IL23R rs6660226 GG · IL1A rs35145107 GG · B3GNT2 rs12467814 AA · PCGF3 rs4690319 GG · PLEKHH2 rs6544659 AA · IRF8 rs6540239 CT
·IgA Nephropathy
Typical likelihood
In line with the general population
NRBF2 rs57917667 GG · OVOL1 rs10896045 AA · IRF4 rs12201499 CC · HP rs10492815 AA · FAM91A1 rs34354351 TT · RREB1 rs12530084 CC · GPN3 rs56838584 GA · PSD3 rs2410596 CC
·TNF
Typical levels
In line with the general population
CRISPLD2 rs118135095 GG · TRIB2 rs116434579 GG · TNF rs1799724 TC · ROBO1 rs149420276 AG · TNF rs1800629 GG · SPRY1 rs115669577 GG · ERICH1 rs138808635 CC · PSD3 rs79105320 GG
·White Blood Cells
Typical levels
In line with the general population
PTPN22 rs2476601 GG · MICB rs2524079 AG · TET2 rs199741557 IA · JAML rs143034248 CC · TTC28 rs62237617 CC · ACKR1 rs34599082 CC · EHD3 rs184409696 GG · ORMDL3 rs4795415 CC
·Eosinophils
Typical levels
In line with the general population
GATA2 rs6782812 AA · SH2B3 rs7310615 GG · SLC22A5 rs2706334 TT · HLA-DQA2 rs28383314 CC · LGALS14 rs412884 CC · HBS1L rs9389268 GG · IL18R1 rs9807989 TC · KLF3 rs73232890 GA
·Monocytes
Typical levels
In line with the general population
LPAR1 rs115162333 TG · B3GNTL1 rs9902102 CC · CEBPG rs12151289 GC · CKM rs73036517 GA · IL17RA rs140221307 TT · FLT3 rs76428106 TT · GFI1 rs150649461 GG · TNFRSF13B rs34557412 AA
·Neutrophils
Typical levels
In line with the general population
ORMDL3 rs3826331 CC · LYST rs1886654 CC · CSF3R rs3917932 GG · NCLN rs144284241 CC · JAML rs143034248 CC · IFNA13 rs142938197 CC · DARS1 rs11548872 GG · PREX1 rs144582521 TT
·Erythrocyte Sedimentation Rate
Typical levels
In line with the general population
CD55 rs12034383 AG
·IgE
Typical levels
In line with the general population
ERMP1 rs928413 GG · FCER1A rs2251746 TT · STAT6 rs1059513 TT · NQO1 rs6499255 AA · ACKR1 rs13962 GG · LPP rs9290877 TC · IL13 rs20541 GG · SLC22A5 rs1800925 CC
·IL-10
Typical levels
In line with the general population
NNT rs140614282 GG · IKBIP rs1048911 TT · VEGFA rs4349809 GT · SHROOM3 rs143141511 GG · ZNF516 rs9951418 CC · SERPINE2 rs282258 TC · BMP2 rs6085948 GA · NFKBIE rs6458375 CT
·IL-17 (Th17)
Typical levels
In line with the general population
SHPRH rs182530774 CC · EPM2A rs187987903 GG · EPM2A rs13215785 GG · GRM1 rs117785887 TT · GRM1 rs35548402 AA · MCFD2 rs1446499 TT · TRIB3 rs62191444 GG · PCDH8 rs9568764 CG
·HLA-B (Autoimmune)
Typical
In line with the general population
HLA-C rs13202464 AA · MICA rs116488202 CC
·HLA-DQ (Inflammation)
Typical activity
In line with the general population
HLA-DQA2 rs9275596 CT · HLA-DQA2 rs9275572 AG · HLA-DQA2 rs9275524 CT · HLA-DQA1 rs2187668 CC
·HLA-DRB1 (Autoimmunity)
Typical
In line with the general population
HLA-DQA2 rs2395185 TG
·HLA-DQA2 (Inflammation)
Typical
In line with the general population
HLA-DQA2 rs9275524 CT
·TLR4 (Inflammation)
Typical activity
In line with the general population
TLR4 rs4986791 CC
·PTPN22 (Autoimmunity)
Typical
In line with the general population
PTPN22 rs2476601 GG
·DAO (Histamine)
Typical activity
In line with the general population
AOC1 rs1049793 GC · AOC1 rs1049742 CC · AOC1 rs2052129 GG
·STAT3 (Th1/Th17)
Typical activity
In line with the general population
STAT3 rs4796793 CC · STAT3 rs2293152 GC · STAT3 rs744166 AA
·TNF Gene (Inflammation)
Typical activity
In line with the general population
CRISPLD2 rs118135095 GG · TRIB2 rs116434579 GG · ATP10B rs149126334 GG · ANO3 rs10834997 GG · TNF rs1800629 GG · ERICH1 rs138808635 CC · GTF2E1 rs10511404 GG
·IL13 (Allergies, Lung Function)
Typical activity
In line with the general population
IL13 rs20541 GG · SLC22A5 rs1800925 CC · SLC22A5 rs1295686 CC · SLC22A5 rs848 CC
·IL4 (Allergies, Autoimmunity)
Typical activity
In line with the general population
SLC22A5 rs2243250 CC
·CRP Gene
Typical activity
In line with the general population
CRP rs1205 CC
·PADI4 (Autoimmune)
Typical activity
In line with the general population
PADI4 rs2240335 AC · PADI4 rs2301888 AG · PADI4 rs2240336 TC
·IL10 Gene (Autoimmunity)
Typical activity
In line with the general population
IL19 rs3024498 TT · FCMR rs3024493 AC · IL19 rs3024505 AG · IL19 rs3024496 GA · IL19 rs1800896 CT
·SLC22A4 (Gut Inflammation)
Typical genetics
In line with the general population
SLC22A4 rs1050152 TC