Marrow
Genomics · Genetic Reports · Precision Wellness

Joint & Tendon Health

Personalized Genetic Report
Joint HealthTendon HealthJoint Health Genes
Sample ClientReport date: 29 July 2026
Genomics · Genetic Reports · Precision Wellness
Marrow Health Laboratories
Marrow
Accession #: MRW-26-5012AC
Report type: Full Report
Report status: FINAL

Specimen and client information

Client
Sample Client
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
Accession
MRW-26-5012AC
Panel
Joint & Tendon Health
Results scored
27
Need attention
8
Report
Full Report

What this report covers

Joint Health · Tendon Health · Joint Health Genes

About this report

This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.

What each result group means

Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.

Your results at a glance

How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 27 results here, 8 came back worth discussing with a clinician and 5 came back in your favour. Bring this document to your appointment.
Worth a conversation with your doctor  (8)These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
From your Joint & Tendon Health report
AHeel Pain (Plantar Fasciitis)
More likely
Higher predisposition than 99% of people
NQO1 rs62051384 CC
ANeck Arthritis
More likely
Higher predisposition than 98% of people
AShoulder Impingement
More likely
Higher predisposition than 90% of people
RFC3 rs7139664 AG · C5ORF63 rs145648292 GG · S100A12 rs143640806 AA · LONRF1 rs17769850 TT · FRMPD4 rs144371252 A · KBTBD3 rs505416 GG · PLCB1 rs6140637 AA · EGFLAM rs60486174 TT
ADisc Degeneration
More likely
Higher predisposition than 90% of people
ZEB1 rs2484990 CC · ZEB1 rs1250307 AA · ZEB1 rs2484992 CC · EYS rs11754641 CC · DCT rs9301951 TT · LRRN1 rs17034687 CC · CILP rs2073711 AG · PSMB9 rs2187689 TC
ATrigger Finger
More likely
Higher predisposition than 87% of people
TNP1 rs10203066 GG · LTBP3 rs4244811 GA · CENPK rs2087927 GA · POLE2 rs3218791 GT · FTO rs10521304 TT · NQO1 rs3790086 GC · KLHL1 rs59988404 GG
AJaw Disorders (TMJ)
More likely
Higher predisposition than 81% of people
BAHCC1 rs1531554 CC · RXFP2 rs60249166 TC · ANKK1 rs1800497 GA · HTR2A rs6313 GA · EPHA5 rs201194999 CC · COL11A1 rs2622873 TT · ICA1L rs62182810 AA · SFRP1 rs10092633 GG
ADupuytren’s Contracture
More likely
Higher predisposition than 80% of people
MAFB rs12481661 GG · WNT7B rs117707689 CC · RAB31 rs11665156 CC · DUXA rs11672486 TT · MAFB rs181089987 TT · KDR rs73818546 GG · SULF1 rs2162353 GG · MAFB rs58716951 CC
ASpinal Arthritis
More likely
Higher predisposition than average
SOX5 rs148034983 TT · KCNC2 rs77092580 AA · LRPAP1 rs11735173 CC · DACH1 rs7982150 AA · MUL1 rs72649149 CC · FAM120B rs875421 TT · SUMF1 rs314440 GG · XYLT1 rs59587833 AG
Running above the typical range  (1)Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
From your Joint & Tendon Health report
HMMP1 (Collagen)
Higher activity
Above the typical range
MMP1 rs1799750 TT
Running below the typical range  (0)Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Nothing in this group.
Working in your favour  (5)Good news. Your genetics look protective or better than average here.
From your Joint & Tendon Health report
FTendon Inflammation
Less likely
Lower predisposition than 81% of people
TNP1 rs10203066 GG · LTBP3 rs4244811 GA · CENPK rs2087927 GA · POLE2 rs3218791 GT · FTO rs10521304 TT · NQO1 rs3790086 GC · KLHL1 rs59988404 GG
FTendon Injury
Less likely
Lower predisposition than 82% of people
POLE2 rs3218791 GT · GJA1 rs11154027 CC · CERS5 rs57224706 AA
FJoint Pain
Less likely
Lower predisposition than 99% of people
SRR rs216175 AA · ERI1 rs330050 GG · LYZ rs317630 TT · DPEP1 rs1126464 GG · FAM53A rs798726 CT · ANAPC4 rs34811474 GA · TGFB2 rs2785988 CA · LTBP1 rs2061027 GA
FEhlers-Danlos Syndrome (Progeroid
Less likely
Lower predisposition than average
FADAMTS5 (Joint Health)
Better genetics
Lower predisposition than average
ADAMTS5 rs2249350 AC · ADAMTS5 rs229052 AG · ADAMTS5 rs162502 TC · ADAMTS5 rs151058 CT · ADAMTS5 rs3171407 CC · ADAMTS5 rs229077 TT · ADAMTS5 rs229071 AA · ADAMTS5 rs162509 CC
In line with most people  (13)Nothing unusual. These were tested and came back typical — worth having on record.
From your Joint & Tendon Health report
·Achilles Tendon Injury
Typical likelihood
In line with the general population · 79th percentile
COL1A1 rs1800012 AC · MMP1 rs591058 CC · VEGFA rs699947 AC · FCN2 rs1134170 TT · COL5A1 rs12722 TC · TMEM158 rs183364169 CC · DPP6 rs4067493 CC · TRIML1 rs60713544 GG
·Hip Pain
Typical likelihood
In line with the general population · 64th percentile
KAZN rs549908604 AA · HIPK1 rs149055514 AA · PBX1 rs506068 CC · PGLYRP3 rs117034852 TT · SEMA4A rs531735825 CC · FNDC7 rs181938434 GG · PGLYRP3 rs118113194 CC · KIAA1614 rs144390511 CC
·Gout
Typical likelihood
In line with the general population · 58th percentile
SLC2A9 rs16890979 CC · SLC2A9 rs6449213 TT · SLC2A9 rs12498742 AA · SPP1 rs2728127 AA · TMEM171 rs520007 CC · TRMT112 rs2078267 TC · GCKR rs1260326 TC · MTX1 rs760077 TA
·Carpal Tunnel Syndrome
Typical likelihood
In line with the general population · 56th percentile
UMPS rs4678145 GG · LNPK rs847139 CC · EFEMP1 rs3791679 AG · ADAMTS14 rs747141 GA · TBX18 rs62422907 AG · TNP1 rs1863190 TA · AEBP1 rs55841377 CG · AOC1 rs6977081 TG
·Rheumatoid Arthritis
Typical likelihood
In line with the general population · 40th percentile
HLA-DQA2 rs6457617 TC · CTLA4 rs3087243 GG · ANKRD55 rs7731626 GG · ETS1 rs73013527 CC · RUNX1 rs8133843 AA · LBH rs7579944 CC · PODXL rs11761231 CC · ARID5B rs71508903 CT
·Joint Stiffness
Typical likelihood
In line with the general population · 39th percentile
·Knee Pain
Typical likelihood
In line with the general population · 36th percentile
COL27A1 rs919642 AA · EPHA5 rs201194999 CC · COL11A1 rs2622873 TT · ICA1L rs62182810 AA · BRINP3 rs72727240 TT · MAB21L3 rs79678808 AA · CDC42BPA rs56339347 AA · CDC42BPA rs573881227 CC
·Tendon Lining Inflammation
Typical likelihood
In line with the general population · 36th percentile
CENPK rs2087927 GA · POLE2 rs3218791 GT · FTO rs10521304 TT · NQO1 rs3790086 GC · KLHL1 rs59988404 GG
·Lupus
Typical likelihood
In line with the general population · 12th percentile
IRF8 rs11644034 GG · NADSYN1 rs3794060 CC · PRDM1 rs6568431 AA · IKZF1 rs4917014 TT · LYST rs9782955 CC · ZFP36L1 rs4902562 AA · UBE2L3 rs7444 CT · SLU7 rs2431697 TC
·Psoriatic Arthritis
Typical likelihood
In line with the general population
TYK2 rs34536443 GG · MICB rs13191343 TC · IL12B rs4921482 TT · STAT2 rs2020854 TT · IL12B rs62377586 GG · SLC22A5 rs848 CC · NXPE3 rs4683946 GG · CNTN4 rs17194140 TT
·Rheumatic Fever
Typical likelihood
In line with the general population
·Ankylosing Spondylitis
Typical likelihood
In line with the general population
IL23R rs11209026 GG · ERAP2 rs10045403 AA · NKX2-3 rs11190133 CC · ERAP1 rs30187 CT · CARD9 rs1128905 CC · INAVA rs41299637 TG · ETS2 rs2836883 AG · ERAP2 rs2910686 CT
·COL5A1 (Collagen)
Typical activity
In line with the general population
COL5A1 rs12722 TC

Methodology

Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.

Limitations

This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.

Performing laboratory & attestation
Performing laboratoryGene by Gene, Ltd.
Laboratory address1445 North Loop West, Suite 760, Houston, TX 77008
CLIA certificationCLIA #45D1102202
CAP accreditationCAP #7212851 · accredited through 7 October 2027
Laboratory DirectorFeng Zhou, PhD, MB(ASCP)
Specimen typeBuccal (cheek) swab — genomic DNA
AccessionMRW-26-5012AC
Date reported29 July 2026

This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-5012AC · © 2026 Marrow Health.