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Genomics · Genetic Reports · Precision Wellness

Longevity & Healthy Aging

Personalized Genetic Report
Longevity & Healthy AgingConditions Affecting LongevityLongevity MarkersLongevity Genes
Sample ClientReport date: 29 July 2026
Genomics · Genetic Reports · Precision Wellness
Marrow Health Laboratories
Marrow
Accession #: MRW-26-52007B
Report type: Full Report
Report status: FINAL

Specimen and client information

Client
Sample Client
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
Accession
MRW-26-52007B
Panel
Longevity & Healthy Aging
Results scored
29 of 33
Need attention
5
Report
Full Report

What this report covers

Longevity & Healthy Aging · Conditions Affecting Longevity · Longevity Markers · Longevity Genes

About this report

This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.

What each result group means

Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.

Your results at a glance

5Worth a conversation with your doctor1Running above the typical range2Running below the typical range4Working in your favour17In line with most people
How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 29 results here, 5 came back worth discussing with a clinician and 4 came back in your favour. Bring this document to your appointment.
Worth a conversation with your doctor  (5)These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
From your Longevity & Healthy Aging report
AArtery Hardening
More likely
Higher predisposition than 95% of people
PEMT rs12936587 GA · NOS3 rs2070744 TC · ZNF668 rs9923231 TC · CDKN2A rs4977574 GG · COMT rs4680 AG · CETP rs5882 AG · ICAM1 rs5498 AG · COMT rs4633 TC
AProstate Cancer
More likely
Higher predisposition than 94% of people
FSTL5 rs7691481 CC · FGF9 rs781386326 GG · GINS4 rs56336841 CC · KCND2 rs73429913 CC · TNFSF11 rs532873142 CC
AFrailty
More likely
Higher predisposition than 89% of people
SYT14 rs12739243 TT · LRPPRC rs4952693 CC · RBM6 rs2071207 TT · TMOD2 rs17612102 CC · PIK3C3 rs8089807 CT · MDFIC rs2396766 AG · NLGN1 rs583514 CT · CCDC6 rs4146140 TC
AColorectal Cancer
More likely
Higher predisposition than 73% of people
ACTL8 rs11203467 GG · PRICKLE1 rs11610543 GG · LRP1 rs7398375 CC · GRM7 rs2163735 GG · CHRDL2 rs3824999 GG · SMAD7 rs4939827 TC · PREX1 rs6066825 GA
APPARD (Longevity)
Worse
Higher predisposition than average
Running above the typical range  (1)Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
From your Longevity & Healthy Aging report
HCFH (Eye Health/ Longevity)
Higher activity
Above the typical range
CFH rs2274700 AA
Running below the typical range  (2)Your genetics point to these sitting lower than average. Same idea — context, not alarm.
From your Longevity & Healthy Aging report
LADA (Cognition/Longevity)
Lower activity
Below the typical range
ADA rs73598374 TC
LCETP (Cholesterol/ Longevity)
Lower activity
Below the typical range
CETP rs5882 AG · CETP rs708272 AA
Working in your favour  (4)Good news. Your genetics look protective or better than average here.
From your Longevity & Healthy Aging report
FCognitive Decline
Less likely
Lower predisposition than 99% of people
CDCA7 rs182734936 CC · ANXA5 rs141005242 CC · TEK rs147486058 AA · DUSP15 rs6089150 CC · CTBP2 rs61869228 CC · HHEX rs60320343 AA · CRP rs1205 CC · FOXO3 rs4946936 CC
FMuscle Loss
Less likely
Lower predisposition than average
KHDC1L rs6453647 CG · TTC9 rs148532338 CC · FDFT1 rs191172273 TT · PPARGC1A rs145583424 GG · LRP1B rs74659977 TT · ZNF622 rs31574 AA · FADS2 rs97384 CC
FLung Cancer
Less likely
Lower predisposition than average
FCHO2 rs42775 CT · ZRANB1 rs76972397 TT · MAP7 rs3799451 AA · OSBPL1A rs482962 CC · EML4 rs7593032 TT
FIGF1R (Longevity)
Better
Lower predisposition than average
IGF1R rs2229765 AA
In line with most people  (17)Nothing unusual. These were tested and came back typical — worth having on record.
From your Longevity & Healthy Aging report
·Aging Eyes
Typical likelihood
In line with the general population · 77th percentile
·Alzheimer's Disease
Typical likelihood
In line with the general population · 65th percentile
CD55 rs3818361 GA · POLR2E rs12151021 AA · HLA-DRB1 rs9271192 AC · SORT1 rs11102972 TC · CLNK rs6846529 CT · COX7C rs62374257 CT · CPSF3 rs72777026 AG · IGHG3 rs7157106 GA
·Cardiovascular Disease
Typical likelihood
In line with the general population · 60th percentile
COMT rs4680 AG · PCSK9 rs11591147 GG · ATG16L1 rs10210302 TT · IRGM rs1000113 TC · LDLR rs6511720 GG · SORT1 rs12740374 GG · PHACTR1 rs9349379 GG
·Age-Related Macular Degeneration
Typical likelihood
In line with the general population · 44th percentile
NECTIN2 rs2075650 AA · MBL2 rs6480975 CC · APOE rs4420638 AA · PRDM1 rs7750345 AA · VEGFA rs943080 TT · MCUB rs4698775 GG · GLI2 rs6721654 TC · NT5DC1 rs3812111 TT
·Facial Wrinkles
Typical
In line with the general population
SIK2 rs11213999 CC · TPGS2 rs78569750 GG · SYNDIG1 rs184605088 CC · NUDT12 rs112608607 TT · LINGO2 rs117828793 CC · BBX rs1283106 CA · BMP6 rs382029 TA · MON1B rs62047859 TT
·Longevity
Typical
In line with the general population
STN1 rs10786775 CC · TERT rs4449583 CC · SIRT1 rs7896005 GA · GSTO1 rs9420907 AA · TERT rs7705526 CA · TERT rs2853677 AG · FOXO3 rs4946936 CC · FOXO3 rs9398171 TT
·Healthy Aging
Typical
In line with the general population
APOE rs7412 CC · NECTIN2 rs157581 TT · DHX58 rs34891485 TT · IRF4 rs12203592 CC · AFF3 rs78438918 AA · ZBTB46 rs6062322 AA · TAPBP rs9277988 TT · ADD1 rs16843603 TT
·Hair Graying
Typical
In line with the general population
NSMCE1 rs1127228 TC · PRDM8 rs7680591 AT
·Pancreatic Cancer
Typical likelihood
In line with the general population
ABO rs505922 CC · NR5A2 rs3790844 AA · MKLN1 rs6971499 TT · CLPTM1L rs401681 TT · BCAR1 rs7190458 AG · GRP rs1517037 CC · MYC rs10094872 AT · ARL6IP6 rs12478462 GT
·SIRT1 (Longevity)
Typical activity
In line with the general population
SIRT1 rs7895833 AA · SIRT1 rs3758391 CT
·TERT (Longevity)
Typical activity
In line with the general population
TERT rs7705526 CA · TERT rs2736100 AC · TERT rs10069690 CT · TERT rs13167280 AG · TERT rs2853677 AG · TERT rs4975605 CC · TERT rs33961405 GG · CLPTM1L rs2853669 AA
·OBFC1 (Longevity)
Typical activity
In line with the general population
GSTO1 rs4387287 CC · SLK rs9419958 CC · GSTO1 rs9420907 AA
·AKT1 (Longevity)
Typical genetics
In line with the general population
AKT1 rs3803304 CC
·APOC3 (Blood Lipids/ Longevity)
Typical activity
In line with the general population
SIDT2 rs2542052 AC · PCSK7 rs5128 CC
·FOXO3 (Longevity)
Typical activity
In line with the general population
FOXO3 rs17069665 AA · FOXO3 rs9398171 TT · FOXO3 rs3800230 TT · FOXO3 rs2764264 TT · ARMC2 rs6911407 AA · FOXO3 rs2802292 GG · ARMC2 rs768023 GG · FOXO3 rs2802288 AA
·TAS2R16 (Bitter Taste/ Longevity)
Typical activity
In line with the general population
·PARP1 (Longevity, Cognition)
Typical genetics
In line with the general population
PARP1 rs3219090 TT

Methodology

Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.

Limitations

This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.

Performing laboratory & attestation
Performing laboratoryGene by Gene, Ltd.
Laboratory address1445 North Loop West, Suite 760, Houston, TX 77008
CLIA certificationCLIA #45D1102202
CAP accreditationCAP #7212851 · accredited through 7 October 2027
Laboratory DirectorFeng Zhou, PhD, MB(ASCP)
Specimen typeBuccal (cheek) swab — genomic DNA
AccessionMRW-26-52007B
Date reported29 July 2026

This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-52007B · © 2026 Marrow Health.