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Genomics · Genetic Reports · Precision Wellness

Mood & Mental Health

Personalized Genetic Report
Mood & EmotionsStress & AnxietyMental HealthBrain Chemicals & Genes
Sample ClientReport date: 29 July 2026
Genomics · Genetic Reports · Precision Wellness
Marrow Health Laboratories
Marrow
Accession #: MRW-26-E4ACDF
Report type: Full Report
Report status: FINAL

Specimen and client information

Client
Sample Client
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
Accession
MRW-26-E4ACDF
Panel
Mood & Mental Health
Results scored
58 of 65
Need attention
14
Report
Full Report

What this report covers

Mood & Emotions · Stress & Anxiety · Mental Health · Brain Chemicals & Genes

About this report

This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.

What each result group means

Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.

Your results at a glance

How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 58 results here, 14 came back worth discussing with a clinician and 4 came back in your favour. Bring this document to your appointment.
Worth a conversation with your doctor  (14)These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
From your Mood & Mental Health report
AMania
More likely
Higher predisposition than 99% of people
AEating Disorders
More likely
Higher predisposition than 99% of people
RASGRF2 rs138206701 AA · OPTN rs10906233 CC · MAGI3 rs61742849 GG · OLIG1 rs117124364 CC · PCDH7 rs74879986 GG · C4ORF17 rs148915469 CA · NKAIN3 rs142014203 TT · CHODL rs77600076 AA
ABinge Eating
More likely
Higher predisposition than 98% of people
SYNDIG1 rs76087671 CC · SLC25A26 rs145763646 GG · FTO rs9939609 TT · MC4R rs17782313 TT · ARHGAP8 rs726170 CC
AGuilty Feelings
More likely
Higher predisposition than 96% of people
ARNTL rs55769038 GG · ELAVL2 rs10119773 GG · H3C12 rs200988 TT · DRD2 rs12420205 TT · BTN3A2 rs9467707 GG · SLC17A1 rs9461218 GG · TTC12 rs10789942 AA · H4C13 rs149949 TT
ABorderline Personality
More likely
Higher predisposition than 93% of people
DPYD rs187785463 GG · MYCN rs57726666 AA · SKP2 rs34416917 GG · SYT1 rs11110253 AA · FAM155A rs9520569 TT · TRDN rs2145737 TT · SNX9 rs6922614 TC · GAP43 rs283386 GA
AObsessive-Compulsive Tendencies
More likely
Higher predisposition than 92% of people
PCDH18 rs11735612 AA · FAM76B rs11021169 GG · CLN5 rs11149058 TT · ANKRD18A rs10973956 AC · FANCL rs35881094 GT · TRPC4 rs6563569 CT · SSH2 rs6354 TT · DLC1 rs75216060 AA
AAnger
More likely
Higher predisposition than 90% of people
PLEK rs7578047 AA · E2F3 rs555017 AA · TRIM31 rs2844775 GG · CSE1L rs6012564 GG · UQCRFS1 rs8102754 TT · DPY19L1 rs6954895 TC · QSER1 rs16924133 AA · ABAT rs1299926 AA
APsychological Trauma
More likely
Higher predisposition than 90% of people
CRHR2 rs2267715 AA · UST rs10457838 TC · RORA rs8041061 TG · RGS2 rs4606 CC · ANKK1 rs1800497 GA · TBC1D2 rs7866350 GC · FBLL1 rs10038727 GA · SH2D1B rs386231 TC
AAgoraphobia
More likely
Higher predisposition than 88% of people
ALow Mood
More likely
Higher predisposition than 85% of people
TCF4 rs1452787 AG · FKBP4 rs2302729 CC · TULP1 rs9296158 GG · FAM53B rs35936514 CC · ANKK1 rs1800497 GA · OXTR rs2254298 GA · FAAH rs324420 CA · TPH1 rs1799913 GT
ABipolar Disorder
More likely
Higher predisposition than 75% of people
NRN1 rs4960155 CT · DUSP28 rs2953145 CC · DCTN5 rs420259 AA · ARVCF rs165599 AG · BCR rs131690 GG · CMTM8 rs4276227 CC · TDRD9 rs11622475 CC · WHRN rs10982256 TT
AEmotional Blindness
More likely
Higher predisposition than average
ANPAS2 (Mood/ Sleep Schedule)
Worse genetics
Higher predisposition than average
NPAS2 rs2305160 GG · NPAS2 rs11123857 AA
AGAD1 (Glutamate/GABA)
Worse
Higher predisposition than average
GAD1 rs3749034 GG
Running above the typical range  (6)Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
From your Mood & Mental Health report
HIrritability
Higher
Higher than 95% of people
CAMKMT rs343949 AA · DPYD rs4411173 AA · TCF4 rs4570961 TC · AMT rs4499638 GC · SIM1 rs9403716 AG · MSRA rs17151565 CG · LRP12 rs4734804 AG · BBX rs507078 GT
HMAOB (Dopamine/ Norepinephrine)
Higher activity
Above the typical range
MAOB rs3027452 G · MAOB rs2283729 G
HDRD3 (Dopamine/Energy)
Higher activity
Above the typical range
DRD3 rs6280 TT
HHTR1A (Serotonin)
Higher activity
Above the typical range
RNF180 rs6295 GG
HOXTR (Oxytocin)
Higher activity
Above the typical range
OXTR rs1042778 GT · OXTR rs13316193 CT · OXTR rs2254298 GA · OXTR rs53576 GG
HKIBRA/WWC1 (Cognition)
Higher activity
Above the typical range
WWC1 rs17070145 TT
Running below the typical range  (8)Your genetics point to these sitting lower than average. Same idea — context, not alarm.
From your Mood & Mental Health report
LCRHR2 (Stress/HPA Axis)
Lower activity
Below the typical range
CRHR2 rs2267715 AA · CRHR2 rs2190242 AA
LRGS2 (Anxiety)
Lower activity
Below the typical range
RGS2 rs10801153 GG · RGS2 rs4606 CC · RGS2 rs16834831 TG · RGS2 rs1890397 AG · RO60 rs16829458 GG
LCRHR1 (Stress/HPA Axis)
Lower activity
Below the typical range
ARHGAP27 rs4792887 CC
LFKBP5 (Stress/ HPA Axis)
Lower activity
Below the typical range
FKBP5 rs1360780 CC · TULP1 rs9470080 CC · FKBP5 rs9394314 AG
LGABA-A
Lower activity
Below the typical range
GABRG2 rs211037 TT · GABRA6 rs3219151 TT
LSLC6A4 (Fatigue, Mental Health)
Lower activity
Below the typical range
BLMH rs2066713 GG
LDRD2 (Dopamine)
Lower activity
Below the typical range
LFAAH (Cannabinoids)
Lower activity
Below the typical range
FAAH rs324420 CA
Working in your favour  (4)Good news. Your genetics look protective or better than average here.
From your Mood & Mental Health report
FAnhedonia
Less likely
Lower predisposition than average
ESRRG rs12042302 TT · EVI5L rs2335859 TT
FCaffeine-Related Anxiety
Less likely
Lower predisposition than average
FNeurodivergence
Less likely
Lower predisposition than average
SSUH2 rs405182 GG · ESRRB rs201369005 GI · PTP4A3 rs11787216 CC · RSU1 rs45595836 CT · GABBR1 rs740883 AT · CRHR1 rs12942300 AT · XRN2 rs910805 GA · PTBP2 rs2391769 GA
FDelirium
Less likely
Lower predisposition than average
In line with most people  (26)Nothing unusual. These were tested and came back typical — worth having on record.
From your Mood & Mental Health report
·Stress
Typical likelihood
In line with the general population · 74th percentile
SPG7 rs2292954 GG · OXTR rs2254298 GA · MROH2A rs7606893 CA · PDCD6IP rs2053425 AC · DPYSL5 rs12474330 GG · PSMD7 rs7193343 TT · CDH12 rs1545967 TA · BDNF rs6265 TC
·Phobias
Typical likelihood
In line with the general population · 74th percentile
ESR1 rs9340799 GA
·Hair Pulling
Typical likelihood
In line with the general population · 74th percentile
·Worrying
Typical likelihood
In line with the general population · 70th percentile
ITIH4 rs6798941 CC · ITIH4 rs12489490 CC · MC4R rs58084604 CC · STAG1 rs6791142 CC · MSL2 rs1729951 GG · CADM2 rs62250713 GA · CADM2 rs1551042 CA · TNXB rs2269426 AG
·Seasonal Low Mood
Typical likelihood
In line with the general population · 65th percentile
PTGER3 rs113067418 CC · MYO16 rs9559377 AA · PSAP rs61852182 CC · DGKB rs190675597 GA · CAMKMT rs17498753 AA · POLR2M rs1808478 TC · MAP3K1 rs3936510 TG · HLCS rs2835490 TT
·Schizophrenia
Typical likelihood
In line with the general population · 63th percentile
DPYD rs1702294 CC · PILRB rs41295924 CC · EDEM3 rs78444298 GG · ELAPOR2 rs137881681 GG · OR4C12 rs139161789 GG · DLC1 rs143092720 GG · RD3 rs117251211 GG · ARSA rs113706174 CC
·Anxiety
Typical likelihood
In line with the general population · 57th percentile
ATP8B4 rs2413998 AA · DNAH8 rs4714177 AA · NUP107 rs11177321 GG · PREPL rs1067327 CC · RNF180 rs6295 GG · IL20RB rs17374749 GG · C6ORF118 rs9295300 AA · NOX4 rs17221829 CC
·Panic Attacks
Typical likelihood
In line with the general population · 57th percentile
TMEM132D rs11060369 AA · LGSN rs6914428 GG · SNURF rs2554444 TA · BLMH rs140701 TT · BLMH rs4583306 GG · SSH2 rs6354 TT · TPH1 rs1800532 GT · COMT rs4680 AG
·SNAP25 (Mental Health)
Typical activity
In line with the general population · 50th percentile
SNAP25 rs3746544 GT · SNAP25 rs363039 GA · SNAP25 rs362987 AC
·Aggression
Typical
In line with the general population · 46th percentile
QSER1 rs16924133 AA · TRIM31 rs2844775 GG · CSE1L rs6012564 GG · ABAT rs1299926 AA · GREM2 rs16840114 AA · PLEK rs7578047 AA · FYN rs2148710 CC · PNLIP rs12249434 CC
·Psychosis
Typical likelihood
In line with the general population · 46th percentile
·Social Anxiety
Typical likelihood
In line with the general population · 37th percentile
·Tics
Typical likelihood
In line with the general population · 33th percentile
OTUD1 rs191044310 TT · CSMD3 rs117648881 GG · FAM76B rs11021169 GG · XYLT1 rs74772983 AA · CLN5 rs11149058 TT · TSPYL5 rs117780640 CC · CCDC66 rs6445765 CC · SGPP2 rs1865896 GG
·GRIA3 (Sleep/Mood)
Typical activity
In line with the general population
GRIA3 rs687577 C
·Nervousness
Typical
In line with the general population
MTCH2 rs11039391 GG · MC4R rs11665052 AA · DLST rs17093914 CC · C1QTNF4 rs34467936 AG · CADM2 rs9854869 CA · CADM2 rs35344466 AC · CADM2 rs7611991 GA · DENND1A rs6478623 GT
·Cortisol
Typical levels
In line with the general population
CNTNAP5 rs11899245 TC · FKBP5 rs1360780 CC · DGKH rs1170109 GT · PDE10A rs2983496 AG · LDLR rs5927 GA · ZFP42 rs6849009 CC · INHBA rs10244501 CC · TFAP2C rs6069930 GG
·Response to Stress (Functional)
Typical response
In line with the general population
COMT rs4680 AG · BDNF rs6265 TC · ARHGAP27 rs4792887 CC · RGS2 rs4606 CC · MAPT rs12944712 GG · CRHR2 rs2267715 AA · HTR2A rs6313 GA · HTR2A rs6311 CT
·ADORA2A (Anxiety)
Typical activity
In line with the general population
ADORA2A rs5751876 CT · ADORA2A rs2298383 TC
·Nail Biting
Typical likelihood
In line with the general population
·GSK3B (Serotonin)
Typical activity
In line with the general population
GSK3B rs334558 AG · LRRC58 rs3755557 TT
·HTR2A (Serotonin)
Typical activity
In line with the general population
HTR2A rs6311 CT
·TPH2 (Serotonin)
Typical activity
In line with the general population
·CNR1 (Cannabinoids)
Typical activity
In line with the general population
CNR1 rs806380 AA · CNR1 rs2023239 CC
·SLC6A2 (Mental Health)
Typical activity
In line with the general population
SLC6A2 rs28386840 TA · CES1 rs2242447 CT · SLC6A2 rs3785143 CC · SLC6A2 rs3785157 CC
·DBH (Mental Health)
Typical activity
In line with the general population
DBH rs1611115 CC · DBH rs1108580 GG
·SLC6A3 (Mental Health)
Typical activity
In line with the general population
LPCAT1 rs27072 CC · SLC6A3 rs6347 TT · SLC6A3 rs2550948 CT · SLC6A3 rs27048 TT

Methodology

Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.

Limitations

This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.

Performing laboratory & attestation
Performing laboratoryGene by Gene, Ltd.
Laboratory address1445 North Loop West, Suite 760, Houston, TX 77008
CLIA certificationCLIA #45D1102202
CAP accreditationCAP #7212851 · accredited through 7 October 2027
Laboratory DirectorFeng Zhou, PhD, MB(ASCP)
Specimen typeBuccal (cheek) swab — genomic DNA
AccessionMRW-26-E4ACDF
Date reported29 July 2026

This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-E4ACDF · © 2026 Marrow Health.