Marrow
Genomics · Genetic Reports · Precision Wellness

Perimenopause

Personalized Genetic Report
Symptoms & ComplaintsHealth RisksLab Markers
Sample ClientReport date: 29 July 2026
Genomics · Genetic Reports · Precision Wellness
Marrow Health Laboratories
Marrow
Accession #: MRW-26-54C1D4
Report type: Full Report
Report status: FINAL

Specimen and client information

Client
Sample Client
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
Accession
MRW-26-54C1D4
Panel
Perimenopause
Results scored
27
Need attention
4
Report
Full Report

What this report covers

Symptoms & Complaints · Health Risks · Lab Markers

About this report

This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.

What each result group means

Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.

Your results at a glance

How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 27 results here, 4 came back worth discussing with a clinician and 3 came back in your favour. Bring this document to your appointment.
Worth a conversation with your doctor  (4)These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
From your Perimenopause report
AMenopause Symptoms
More likely
Higher predisposition than 99% of people
AHeavy Sweating
More likely
Higher predisposition than 91% of people
LONP2 rs6500380 GG · SLC6A16 rs149876322 CG · PPP1CB rs56089836 CC · DLG2 rs12280544 CC · TLN2 rs139024759 AA · TUSC1 rs117093392 AA · UBLCP1 rs143772159 CC · FZD8 rs190252627 CC
ASexual Dysfunction
More likely
Higher predisposition than 90% of people
CHSY3 rs13436218 TT · MDGA2 rs1160351 CC · ABCC4 rs117651201 AA · EBF2 rs113716552 CC · S1PR1 rs76296920 AA · NNMT rs145841294 GG · FNDC3A rs78447716 AA
ALow Mood
More likely
Higher predisposition than 85% of people
TCF4 rs1452787 AG · FKBP4 rs2302729 CC · TULP1 rs9296158 GG · FAM53B rs35936514 CC · ANKK1 rs1800497 GA · OXTR rs2254298 GA · FAAH rs324420 CA · TPH1 rs1799913 GT
Running above the typical range  (4)Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
From your Perimenopause report
HIrritability
Higher
Higher than 95% of people
CAMKMT rs343949 AA · DPYD rs4411173 AA · TCF4 rs4570961 TC · AMT rs4499638 GC · SIM1 rs9403716 AG · MSRA rs17151565 CG · LRP12 rs4734804 AG · BBX rs507078 GT
HFSH
Higher levels
Above the typical range
FSHR rs2300441 GA · UBE3A rs4109610 TT · CYP19A1 rs2414095 GG · GAD2 rs8190595 CC · ZNF438 rs187634935 GG · PTER rs116990127 CC · PFKFB3 rs12269260 TT · KLF6 rs183217426 CC
HTestosterone (F)
Higher levels
Above the typical range
CYP3A7 rs45446698 TT · FKBP4 rs56196860 CC · TYK2 rs8111359 CC · NUDT2 rs61237993 AA · AKR1C3 rs36032941 AC · ABCA8 rs34931250 CT · SLC51A rs5855544 IT · MLXIPL rs13229619 GA
HEstradiol
Higher levels
Above the typical range
ESR1 rs2234693 CT · ESR1 rs2077647 CT · UIMC1 rs2454949 AA · DTNB rs199630126 AA · RHNO1 rs28990703 AG · CYP19A1 rs727479 AA · HELB rs75770066 AA · TNP1 rs13387042 GG
Running below the typical range  (0)Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Nothing in this group.
Working in your favour  (3)Good news. Your genetics look protective or better than average here.
From your Perimenopause report
FCognitive Decline
Less likely
Lower predisposition than 99% of people
CDCA7 rs182734936 CC · ANXA5 rs141005242 CC · TEK rs147486058 AA · DUSP15 rs6089150 CC · CTBP2 rs61869228 CC · HHEX rs60320343 AA · CRP rs1205 CC · FOXO3 rs4946936 CC
FOverweight
Less likely
Lower predisposition than 99% of people
LEPR rs1805096 GG · MC4R rs2229616 CC · TCF7L2 rs7903146 CT · NPY rs16147 TT · NEGR1 rs3101336 CC · ADRB2 rs1042713 GA · PEX11A rs894160 CT · NEGR1 rs2815752 AA
FMetabolic Syndrome
Less likely
Lower predisposition than 99% of people
TCF7L2 rs7903146 CT · MTNR1B rs10830963 CG · LPL rs328 CC · WSB2 rs7973260 AG · MLXIPL rs12056034 AG · TRIB1 rs2980888 TC · CLPTM1 rs483082 TG · GALNT2 rs2281721 CT
In line with most people  (16)Nothing unusual. These were tested and came back typical — worth having on record.
From your Perimenopause report
·Vaginal Atrophy
Typical likelihood
In line with the general population · 67th percentile
·Total Cholesterol
Typical levels
In line with the general population · 61th percentile
CETP rs708272 AA · SMARCA4 rs142158911 GG · SORT1 rs12740374 GG · HNF4A rs1800961 CC · APOB rs562338 GG · FLT3 rs76428106 TT · PPP1R3B rs9987289 GG · KIF13B rs117139027 GG
·Cardiovascular Disease
Typical likelihood
In line with the general population · 60th percentile
COMT rs4680 AG · PCSK9 rs11591147 GG · ATG16L1 rs10210302 TT · IRGM rs1000113 TC · LDLR rs6511720 GG · SORT1 rs12740374 GG · PHACTR1 rs9349379 GG
·Anxiety
Typical likelihood
In line with the general population · 57th percentile
ATP8B4 rs2413998 AA · DNAH8 rs4714177 AA · NUP107 rs11177321 GG · PREPL rs1067327 CC · RNF180 rs6295 GG · IL20RB rs17374749 GG · C6ORF118 rs9295300 AA · NOX4 rs17221829 CC
·Type 2 Diabetes
Typical likelihood
In line with the general population · 49th percentile
TCF7L2 rs7903146 CT · SLC30A8 rs13266634 CC · GCKR rs780093 CC · ADCY5 rs11708067 AA · IMPDH1 rs791595 AG · TNF rs2857605 TC · SLC38A11 rs10195252 TC · TSPAN3 rs7177055 GA
·LDL Cholesterol
Typical levels
In line with the general population · 44th percentile
APOE rs141622900 GG · APOE rs7254892 GG · APOB rs693 AG · LDLR rs688 TC · CETP rs5882 AG · LDLR rs6511720 GG · USP24 rs72660594 TT · NECTIN2 rs11668327 GG
·Irregular Periods
Typical likelihood
In line with the general population · 36th percentile
ARL14EP rs11031005 TT · ARL14EP rs74485684 TT · BHLHE41 rs10842700 CG · BORCS7 rs78602818 GG · TPH2 rs374833420 AA · MYOM2 rs188291369 CC
·Osteoporosis
Typical likelihood
In line with the general population · 33th percentile
MARCO rs115242848 CC · COPB1 rs10741657 GG · CPNE1 rs143383 AA · CPED1 rs3779381 AA · ZBTB40 rs34414754 AA · WLS rs2566755 TT · CPED1 rs10242100 AA · FKBP11 rs3741619 GA
·Triglycerides
Typical levels
In line with the general population · 16th percentile
PAFAH1B2 rs186808413 CC · LPL rs117604010 GG · MAU2 rs58542926 CC · MLXIPL rs113296769 AA · CLPTM1 rs483082 TG · SIDT2 rs964184 CC · PCSK7 rs662799 AA
·Sleep Quality
Typical
In line with the general population
KANSL1 rs1107820 TT · VGLL2 rs4946246 TG · RALYL rs118149821 CC · CHRM2 rs146885652 GG · FOXO6 rs2226263 TT · TENM4 rs117191802 AA · TCF21 rs13201465 AA · RALYL rs191939331 GG
·TSH
Typical levels
In line with the general population
LRRC6 rs117764941 GG · NFIA rs334725 AA · PDE8B rs2928167 AA · NR3C2 rs11732089 TT · TBX2 rs1157994 GG · FAM227B rs17477923 TT · VEGFA rs1317983 CT · TNP1 rs13020935 GA
·Vitamin D
Typical need
In line with the general population
COPB1 rs12794714 AA · COPB1 rs10832289 TT · GC rs2282679 GT · VDR rs2228570 GA · PDE3B rs571484036 AA · GC rs222026 TT · GC rs4588 TG · VDR rs731236 AG
·HDL Cholesterol
Typical levels
In line with the general population
SCARB1 rs921919 AA · ABCA8 rs112001035 GA · UBE2L3 rs12158299 TC · VEGFA rs998584 CA · ADAM10 rs2070895 GG · MCUB rs189866430 TT · ARID1A rs193084249 AA · ABCA1 rs2740488 AA
·Fasting Glucose
Typical levels
In line with the general population
GCKR rs780093 CC · CDKN2A rs10811661 TT · CETP rs708272 AA · IMPDH1 rs791595 AG · TNF rs2857605 TC · SLC38A11 rs10195252 TC · DGKB rs2191349 GT · PPARGC1A rs8192678 TC
·Red Blood Cells
Typical levels
In line with the general population
PTPRC rs1434282 TT · TMEM72 rs2281841 CC · SBF2 rs368417629 TG · PPRC1 rs149687130 AA · TTC1 rs148871069 AA · EGLN2 rs184088518 GG · SLC9A3R2 rs139491786 CC · HCRTR2 rs4715517 CC
·Iron
Typical need
In line with the general population
TMPRSS6 rs4820268 GA · TMPRSS6 rs855791 AG · TF rs3811647 AG · DTWD2 rs2442120 CC · SLC24A2 rs142401741 GG · IRX2 rs62330869 AA · HFE rs1799945 CC · SCGN rs115809796 AA

Methodology

Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.

Limitations

This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.

Performing laboratory & attestation
Performing laboratoryGene by Gene, Ltd.
Laboratory address1445 North Loop West, Suite 760, Houston, TX 77008
CLIA certificationCLIA #45D1102202
CAP accreditationCAP #7212851 · accredited through 7 October 2027
Laboratory DirectorFeng Zhou, PhD, MB(ASCP)
Specimen typeBuccal (cheek) swab — genomic DNA
AccessionMRW-26-54C1D4
Date reported29 July 2026

This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-54C1D4 · © 2026 Marrow Health.