Marrow
Genomics · Genetic Reports · Precision Wellness

Addictions

Personalized Genetic Report
General AddictionSubstance Addiction
Sample ClientReport date: 29 July 2026
Genomics · Genetic Reports · Precision Wellness
Marrow Health Laboratories
Marrow
Accession #: MRW-26-A64B38
Report type: Summary Report
Report status: FINAL

Specimen and client information

Client
Sample Client
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
Accession
MRW-26-A64B38
Panel
Addictions
Results scored
5
Need attention
1
Report
Summary Report

What this report covers

General Addiction · Substance Addiction

About this report

This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.

What each result group means

Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.

Your results at a glance

How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 5 results here, 1 came back worth discussing with a clinician and 0 came back in your favour. Bring this document to your appointment.

What this package looks at

Addictions — Addictions are complex conditions that involve a compulsive need to engage in certain behaviors or consume substances, despite negative consequences. While environmental factors, stress, and life experiences contribute to the development of addictions, genetics also plays a

What you can actually do

These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.

Changes you can make yourself

1
Psychotherapy

Schedule and attend regular sessions with a licensed psychotherapist, typically once a week for 50-60 minutes, TA over a period of several months to years depending on your individual needs and progress.

Relates to: Tobacco Addiction
relevance
2
Support Groups

Attend a support group meeting related to your condition at least once a week.

Relates to: Tobacco Addiction
relevance
3
Yoga30 minutes

Practice yoga for at least 20 to 30 minutes a day, most days of the week.

Relates to: DRD2 (Dopamine), Tobacco Addiction
relevance
4
Mindfulness30 minutes

TA seated position, close your eyes, focus on your breathing, and observe your thoughts and sensations without judgment.

Relates to: Tobacco Addiction
relevance
5
Mindfulness Meditation30 minutes

TA focus on your breath, observing thoughts and sensations without judgment.

Relates to: Tobacco Addiction, DRD2 (Dopamine)
relevance
6
Art Therapy

Participate in art therapy sessions, which can include activities such as painting, sculpting, or drawing, for 1-2 TA hours per week.

Relates to: Tobacco Addiction
relevance
7
Hatha Yoga

TA guided sessions for beginners or those unfamiliar with the poses.

Relates to: Tobacco Addiction
relevance
8
Aromatherapy30 minutes

Use a diffuser to disperse the scent into your room TA for 30-60 minutes at a time, up to 3 times a day.

Relates to: Tobacco Addiction
relevance
9
Breathing Techniques10 minutes

Practice deep breathing exercises for 10 minutes daily, preferably in a quiet space where you won't be disturbed.

Relates to: Tobacco Addiction
relevance
10
Chewing

Practice this technique at every meal and with snacks to improve digestion and satiety.

Relates to: Tobacco Addiction
relevance
11
Iyengar Yoga

Choose a class led by a certified Iyengar yoga TA instructor to ensure proper guidance and technique adherence.

Relates to: Tobacco Addiction
relevance

Worth asking your clinician about

These came up in the research behind your flagged results. They are listed by name so you can ask about them. Marrow is not recommending them, and gives no dose. Supplements interact with prescription medication and with each other — that conversation belongs with your clinician.

1
St. John's Wort
Relates to: DRD2 (Dopamine), Tobacco Addiction
relevance
2
Melatonin
Relates to: Tobacco Addiction
relevance
3
Black Pepper
Relates to: Tobacco Addiction
relevance

Your headline findings

Of the 5 results in this package, these 1 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.

Tobacco AddictionMore likely
More likely to be addicted to tobacco based on 1,143,273 genetic variants we looked at
Your risk is greater than 80% of the population and lower than 20% of the population.

What this actually is

Key Takeaways: About 50% of the differences in people's chances of developing tobacco addiction may be due to genetics.

Other risk factors include age, parents and peers who use tobacco, other substance use, mental health issues like depression or PTSD.

About 8% of people in the U.S. aged 12 and older have a nicotine dependence.

What you can do

  • Psychotherapy
    Schedule and attend regular sessions with a licensed psychotherapist, typically once a week for 50-60 minutes, TA over a period of several months to years depending on your individual needs and progress.
  • Support Groups
    Attend a support group meeting related to your condition at least once a week.
  • Yoga 30 minutes
    Practice yoga for at least 20 to 30 minutes a day, most days of the week.
From your Addictions report

Everything else that came back

The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.

Running below the typical range  (1)
  • DRD2 (Dopamine) — Lower activity
In line with most people  (3)
  • Addiction — Typical likelihood, 62th percentile
  • Alcohol Addiction — Typical likelihood, 48th percentile
  • Cannabis Addiction — Typical likelihood, 20th percentile

What to do with this

Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.

Methodology

Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.

Limitations

This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.

Performing laboratory & attestation
Performing laboratoryGene by Gene, Ltd.
Laboratory address1445 North Loop West, Suite 760, Houston, TX 77008
CLIA certificationCLIA #45D1102202
CAP accreditationCAP #7212851 · accredited through 7 October 2027
Laboratory DirectorFeng Zhou, PhD, MB(ASCP)
Specimen typeBuccal (cheek) swab — genomic DNA
AccessionMRW-26-A64B38
Date reported29 July 2026

This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-A64B38 · © 2026 Marrow Health.