Metabolism · Mental Effects · Effects on Appetite
This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.
Cannabinoids — How your body interacts with cannabinoids depends significantly on your unique genetic profile. This analysis explores three key areas that influence individual responses: metabolic processing, neurological effects, and impact on appetite regulation.
These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.
TA seated position, close your eyes, focus on your breathing, and observe your thoughts and sensations without judgment.
Schedule and attend regular sessions with a licensed psychotherapist, typically once a week for 50-60 minutes, TA over a period of several months to years depending on your individual needs and progress.
Practice yoga for at least 20 to 30 minutes a day, most days of the week.
Stop any form of cannabis use, including smoking, vaping, edibles, and topical applications.
Attend a support group meeting related to your condition at least once a week.
Check for lead-based paints in older homes and avoid cooking or storing food in uncoated metal containers.
Consume fewer calories than your body needs for maintenance.
Reduce your intake of saturated fats by choosing lean cuts of meat, opting for low-fat or fat-free dairy products, and using cooking oils high in unsaturated fats (like olive or canola oil) instead of butter or lard.
Practice applied relaxation by dedicating 15-30 minutes each day to learning and practicing relaxation TA techniques, such as deep breathing, progressive muscle relaxation, or guided imagery.
Participate in art therapy sessions, which can include activities such as painting, sculpting, or drawing, for 1-2 TA hours per week.
Engage actively in exercises assigned by your therapist both during sessions and as homework to apply CBT strategies to daily life.
Of the 9 results in this package, these 3 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.
Certain genetic variants may affect the risk and severity of THC-related psychosis.
Carriers of several risk variants may want to consider avoiding cannabis use.
The CNR1 gene encodes the type-1 cannabinoid receptor (CB1), whose activation improves mood and anxiety.
The CNR1 gene encodes the type-1 cannabinoid receptor (CB1), whose activation increases appetite.
The ‘T’ allele of rs806378 is believed to increase CB1 activity.
This variant has been associated with decreased appetite from cannabinoid use (THC, CBD, or their combination) compared to the ‘CC’ genotype.
The CNR1 gene encodes the type-1 cannabinoid receptor (CB1), whose activation increases appetite.
The most studied SNP in this gene is rs1049353 or 1359G/A.
Its minor ‘T’ allele doesn’t change the CB1 receptor structure but is believed to impair gene expression and receptor activity.
The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.
Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.
Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.
This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.
| Performing laboratory | Gene by Gene, Ltd. |
| Laboratory address | 1445 North Loop West, Suite 760, Houston, TX 77008 |
| CLIA certification | CLIA #45D1102202 |
| CAP accreditation | CAP #7212851 · accredited through 7 October 2027 |
| Laboratory Director | Feng Zhou, PhD, MB(ASCP) |
| Specimen type | Buccal (cheek) swab — genomic DNA |
| Accession | MRW-26-45953A |
| Date reported | 29 July 2026 |
This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-45953A · © 2026 Marrow Health.