Specimen and client information
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
Panel
Cardiovascular Health
What this report covers
Heart Health · Brain Vessels · Veins & Other Vessels · Heart Rate · Blood Pressure · Heart Health Genes · Cholesterol & Lab Markers
About this report
This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.
What each result group means
Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.
Your results at a glance
How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 82 results here, 12 came back worth discussing with a clinician and 2 came back in your favour. Bring this document to your appointment.
What this package looks at
Cardiovascular Health — “Oh, my god! That will give you a heart attack!” said every cliche grandmother ever written. There is a notoriously long list for what “that” is, from high cholesterol to stress to weight. Unfortunately, people have a tendency to not worry about a health issue until it becomes a problem. So,
What you can actually do
These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.
Changes you can make yourself
1
Mediterranean DietLimit red meat to a few times a month and include a moderate amount of dairy products.
Relates to: Coronary Artery Disease, Artery Hardening, Peripheral Artery Disease, ApoB
2
Choose Healthy FatsAim for at least two servings of fatty fish per week and use olive oil for cooking and salad dressings.
Relates to: ApoB, Artery Hardening, Coronary Artery Disease, Lipoprotein(a)
3
Walking30 minutesIncorporate at least 30 minutes of brisk walking into your daily routine, aiming for a minimum of five days a week.
Relates to: Coronary Artery Disease, Peripheral Artery Disease, Artery Hardening, ApoB
4
Avoid Secondhand SmokeAvoid Implementing a smoke-free lifestyle involves communicating your needs to family, friends, and coworkers, requesting they respect your choice by smoking away from you.
Relates to: Coronary Artery Disease, Artery Hardening, ApoB, Homocysteine
5
Sleep for 7+ HoursEnsure you allocate enough time in your schedule to achieve a minimum of 7 hours of sleep each night.
Relates to: Coronary Artery Disease, Heart Rate Recovery, Artery Hardening, ApoB
6
Limit Saturated FatReduce your intake of saturated fats by choosing lean cuts of meat, opting for low-fat or fat-free dairy products, and using cooking oils high in unsaturated fats (like olive or canola oil) instead of butter or lard.
Relates to: Artery Hardening, Peripheral Artery Disease, Coronary Artery Disease, Lipoprotein(a)
7
Stair Climbing10 minutesAim for at least 10 minutes of continuous stair climbing or multiple shorter sessions that add up to 10 minutes per day.
Relates to: Coronary Artery Disease, Artery Hardening
8
Eat Fiber-Rich Foodsgrams per day, spread out over all meals.
Relates to: ApoB, Artery Hardening, Coronary Artery Disease, Peripheral Artery Disease
9
DASH DietThis diet should be followed daily to manage blood pressure effectively.
Relates to: Coronary Artery Disease, Heart Failure, Artery Hardening, Peripheral Artery Disease
Worth asking your clinician about
These came up in the research behind your flagged results. They are listed by name so you can ask about them. Marrow is not recommending them, and gives no dose. Supplements interact with prescription medication and with each other — that conversation belongs with your clinician.
1
MethylfolateRelates to: Homocysteine, Retinal Vein Occlusion, Coronary Artery Disease, Artery Hardening
2
Dietary Omega-3 Fatty AcidsRelates to: Heart Failure, Artery Hardening, Coronary Artery Disease, Peripheral Artery Disease
3
Omega-3 (Fish Oil)Relates to: Artery Hardening, Coronary Artery Disease, Homocysteine, Heart Failure
4
GenisteinRelates to: Artery Hardening, Homocysteine, Coronary Artery Disease, Lipoprotein(a)
5
PycnogenolRelates to: Varicose Veins, Coronary Artery Disease, Artery Hardening
Your headline findings
Of the 82 results in this package, these 8 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.
Varicose VeinsMore likely
More likely to have varicose veins based on 81,137 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.
What this actually is
Risk factors include: age, being female, overweight, sitting or standing most of the day, pregnancy, and childbirth.
If you have a high genetic risk, you may reduce overall risk by taking action on risk factors that you can change.
Normal, healthy veins have many valves that keep the blood flowing in the right direction.
What you can do
- Walking 30 minutes
Incorporate at least 30 minutes of brisk walking into your daily routine, aiming for a minimum of five days a week. - Apples
Incorporate at least one whole apple into your daily diet, either as a snack or part of your meals, ensuring to eat them consistently every day for an ongoing period to derive potential health benefits.
Ask your clinician about
Named only. Marrow gives no dose and does not recommend these.
From your Cardiovascular Health report
Blood SpotsMore likely
Higher predisposition than 99% of people
Your result sits higher than 99% of the population.
From your Cardiovascular Health report
PalpitationsMore likely
More likely to have palpitations based on 1,209,944 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.
What this actually is
Key Takeaways: While no heritability percentage exists yet for this condition, genes involved may influence various heart functions.
Other risk factors include stress, anxiety, pregnancy, age, stimulants, overactive thyroid, and heart problems.
Experiencing palpitations are not uncommon, particularly because they can result from causes unrelated to heart conditions, like anxiety.
From your Cardiovascular Health report
Low Blood PressureMore likely
More likely to have low blood pressure based on 54,555 genetic variants we looked at
Your risk is greater than 99% of the population and lower than 1% of the population.
What this actually is
Key Takeaways: Genetics may play a role by influencing nervous system function, kidney function, and hormone activity.
Other risk factors include certain medications and health conditions.
It is estimated that up to 25% of adults may have low blood pressure.
What you can do
- Walking 30 minutes
Incorporate at least 30 minutes of brisk walking into your daily routine, aiming for a minimum of five days a week. - Hazelnuts
Incorporate a handful of hazelnuts (about or) into your diet daily.
From your Cardiovascular Health report
Artery HardeningMore likely
More likely to have atherosclerosis based on 51,588 genetic variants we looked at
Your risk is greater than 95% of the population and lower than 5% of the population.
What this actually is
Key Takeaways: About 60% of differences in people's chances of having atherosclerosis may be due to genetics Risk factors: being male, high blood pressure and cholesterol, diabetes, obesity, smoking, lack of exercise, poor diet, and age.
Artery hardening begins at a young age and your genetics, lifestyle, diet, and exercise may all impact how much and how fast it develops over the course of your lifetime.
The arteries are blood vessels that carry oxygen and nutrients from the heart to the rest of the body.
What you can do
- Mediterranean Diet
Limit red meat to a few times a month and include a moderate amount of dairy products. - Choose Healthy Fats
Aim for at least two servings of fatty fish per week and use olive oil for cooking and salad dressings. - Walking 30 minutes
Incorporate at least 30 minutes of brisk walking into your daily routine, aiming for a minimum of five days a week.
From your Cardiovascular Health report
Retinal Vein OcclusionMore likely
Higher predisposition than 90% of people
Your risk is greater than 90% of the population and lower than 10% of the population.
What this actually is
Retinal Vein Treatment for underlying risk from the blockage. injections of vision, laser reduce inflammation.
Ask your clinician about
- Methylfolate
- Dietary Omega-3 Fatty Acids
- Genistein
Named only. Marrow gives no dose and does not recommend these.
From your Cardiovascular Health report
Coronary Artery DiseaseMore likely
More likely to have coronary artery disease based on 1,049,366 genetic variants we looked at
Your risk is greater than 67% of the population and lower than 33% of the population.
What this actually is
Key Takeaways: Over 18 million people have heart disease in the U.S.
A third of deaths from heart disease are preventable.
Other risk factors include excess weight, stress, sedentary lifestyle, smoking, and more.
What you can do
- Mediterranean Diet
Limit red meat to a few times a month and include a moderate amount of dairy products. - Choose Healthy Fats
Aim for at least two servings of fatty fish per week and use olive oil for cooking and salad dressings. - Walking 30 minutes
Incorporate at least 30 minutes of brisk walking into your daily routine, aiming for a minimum of five days a week.
From your Cardiovascular Health report
Heart FailureMore likely
More likely to have heart failure based on 35,698 genetic variants we looked at
What this actually is
Key risk factors: high blood pressure, diabetes, coronary artery disease, arrhythmias, and infections.
Heart failure affects about 26 million people worldwide, with about 6 million of those in the U.S.
If your genetic risk is high, you may lower your overall risk by taking action on those risk factors that you can change.
What you can do
- DASH Diet
This diet should be followed daily to manage blood pressure effectively. - Hydroxytyrosol And Punicalagin
per day, and for punicalagin, it is about per day.
Ask your clinician about
- Dietary Omega-3 Fatty Acids
Named only. Marrow gives no dose and does not recommend these.
From your Cardiovascular Health report
A further 4 results were also flagged for attention. They are listed below and explained in full in the technical version of this report.
Where your genetics are working for you
Not everything in a genetic report is a warning. These came back protective or better than average.
Metabolic SyndromeLess likely
Less likely to have metabolic syndrome based on 636,870 genetic variants we looked at
Your risk is greater than 1% of the population and lower than 99% of the population.
What this actually is
Factors that might increase the risk of developing metabolic syndrome include: Age: Risk increases with age.
A history of diabetes in one's family.
A history of gestational diabetes or having given birth to a baby weighing more than 9 pounds.
From your Cardiovascular Health report
Mitral Valve ProlapseLess likely
Less likely to have mitral valve prolapse based on 1,668 genetic variants we looked at
What this actually is
Risk factors for mitral valve prolapse include: Being female Connective tissue disorders, like Marfan syndrome or Ehlers-Danlos syndrome Scoliosis or other skeletal problems MVP can sometimes run in families, suggesting a genetic component to the condition.
It is also associated with genetic connective tissue disorders like Marfan syndrome, which is caused by mutations in the FBN1 gene.
Most people with MVP don't need treatment unless the condition is severe or causing significant symptoms.
From your Cardiovascular Health report
Everything else that came back
The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.
Worth a conversation with your doctor (4)
- Myocarditis — More likely
- Subarachnoid Hemorrhage — More likely
- Brain Hemorrhage — More likely
- Peripheral Artery Disease — More likely
Running above the typical range (13)
- ApoB — Higher levels, 99th percentile
- ADRB1 (Cardiovascular) — Higher activity, 92th percentile
- IRS1 (Metabolic Health) — Higher activity, 85th percentile
- Lipoprotein(a) — Higher levels, 81th percentile
- Heart Rate Variability — Higher
- PCSK9 (Cholesterol) — Higher activity
- CELSR2-PSRC1-SORT1 (Cardiovascular) — Higher activity
- AGT (Cardiovascular & Fitness) — Higher activity
- GCH1 (Cardiovascular) — Higher activity
- LIPC (Cardiovascular) — Higher activity
- TMAO — Higher levels
- Homocysteine — Higher levels
- Platelet Aggregation — Higher
Running below the typical range (8)
- Heart Rate Recovery — Slower
- CPS1 (Cardiovascular, Kidney Health) — Lower activity
- DOCK7 (Blood Lipids) — Lower activity
- FABP2 (Blood Sugar/ Cardiovascular) — Lower activity
- CETP (Cholesterol/ Longevity) — Lower activity
- ACE (Fitness/ Cardiovascular) — Lower activity
- MLXIPL (Triglycerides, Cardiovascular) — Lower activity
- SOAT1 (Cholesterol/ Cognition) — Lower activity
In line with most people (47)
- Peripheral Vascular Disease — Typical likelihood, 98th percentile
- Chronic Venous Insufficiency — Typical likelihood, 85th percentile
- Heart Arrhythmia — Typical likelihood, 67th percentile
- POTS — Typical likelihood, 65th percentile
- VLDL Cholesterol — Typical levels, 65th percentile
- Stroke — Typical likelihood, 63th percentile
- Venous Thromboembolism — Typical likelihood, 61th percentile
- Total Cholesterol — Typical levels, 61th percentile
- Cardiovascular Disease — Typical likelihood, 60th percentile
- Chest Pain (Angina) — Typical likelihood, 52th percentile
- Blood Clotting — Typical likelihood, 52th percentile
- High Blood Pressure — Typical likelihood, 51th percentile
- LDL Particle Number (LDL-P) — Typical, 47th percentile
- High Cholesterol — Typical likelihood, 46th percentile
- LDL Cholesterol — Typical levels, 44th percentile
- Atrial Fibrillation — Typical likelihood, 39th percentile
- Cold Hands and Feet (Raynaud's) — Typical likelihood, 31th percentile
- Heart Attack — Typical likelihood
- Rheumatic Heart Disease — Typical likelihood
- Aortic Stenosis — Typical likelihood
- Dilated Cardiomyopathy — Typical likelihood
- Hypertrophic Cardiomyopathy — Typical likelihood
- Aortic Valve Calcification — Typical likelihood
- Aortic Aneurysm — Typical likelihood
- Brain Aneurysm — Typical likelihood
- Cerebral Small Vessel Disease — Typical likelihood
- Brain Ischemia — Typical likelihood
- Vasculitis — Typical likelihood
- Deep Vein Thrombosis — Typical likelihood
- Heart Rate — Typical
- Tachycardia — Typical likelihood
- Bradycardia — Typical likelihood
- Salt Sensitivity — Typical
- Pulmonary Hypertension — Typical likelihood
- APOC3 (Blood Lipids/ Longevity) — Typical activity
- NOS3 (Cardiovascular) — Typical activity
- HMGCR (Cholesterol) — Typical activity
- APOA2 (Weight, Blood Lipids) — Typical activity
- APOB Gene (Cardiovascular) — Typical activity
- ABCA1 (Cholesterol) — Typical genetics
- LPA (Blood Lipids & Heart Health) — Typical activity
- LDLR (Cholesterol, Cardiovascular) — Typical activity
- LDL Particle Size — Typical
- Lp-PLA2 — Typical levels
- Platelets — Typical levels
- Response to Ezetimibe — Typical
- Response to Statins (Functional) — Typical response
What to do with this
Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.
Methodology
Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.
Limitations
This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.