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Genomics · Genetic Reports · Precision Wellness

Hormone Health

Personalized Genetic Report
Thyroid HormonesReproductive HormonesMetabolic HormonesStress HormonesHormone Genes
Sample ClientReport date: 29 July 2026
Genomics · Genetic Reports · Precision Wellness
Marrow Health Laboratories
Marrow
Accession #: MRW-26-6AFD86
Report type: Summary Report
Report status: FINAL

Specimen and client information

Client
Sample Client
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
Accession
MRW-26-6AFD86
Panel
Hormone Health
Results scored
46
Need attention
1
Report
Summary Report

What this report covers

Thyroid Hormones · Reproductive Hormones · Metabolic Hormones · Stress Hormones · Hormone Genes

About this report

This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.

What each result group means

Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.

Your results at a glance

How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 46 results here, 1 came back worth discussing with a clinician and 0 came back in your favour. Bring this document to your appointment.

What this package looks at

Hormone Health — Your hormonal (endocrine) system regulates body processes, such as appetite, sex drive, tissue repair, metabolism, and more. Hormones affect more or less everything in your body!

What you can actually do

These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.

Changes you can make yourself

1
Dietary Protein

Include a variety of protein sources such as meat, fish, eggs, dairy, beans, and nuts in your diet every day, aiming for at least of protein per kilogram of body weight.

Relates to: GLP-1
relevance

Worth asking your clinician about

These came up in the research behind your flagged results. They are listed by name so you can ask about them. Marrow is not recommending them, and gives no dose. Supplements interact with prescription medication and with each other — that conversation belongs with your clinician.

1
Resistant Starch
Relates to: TCF7L2 (Blood Sugar/Diet), GLP-1
relevance
2
Berberine
Relates to: TCF7L2 (Blood Sugar/Diet), GLP-1
relevance
3
Whey Protein
Relates to: TCF7L2 (Blood Sugar/Diet), GLP-1
relevance
4
Cinnamon
Relates to: TCF7L2 (Blood Sugar/Diet), GLP-1
relevance
5
Probiotics
Relates to: GLP-1
relevance
6
Butyrate
Relates to: GLP-1, TCF7L2 (Blood Sugar/Diet)
relevance
7
Chicory
Relates to: GLP-1, TCF7L2 (Blood Sugar/Diet)
relevance
8
Guar Gum
Relates to: GLP-1, TCF7L2 (Blood Sugar/Diet)
relevance
9
Lactobacillus Reuteri
Relates to: GLP-1
relevance
10
Black Seed (Black Cumin)
Relates to: Luteinizing Hormone (LH)
relevance

Your headline findings

Of the 46 results in this package, these 1 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.

TCF7L2 (Blood Sugar/Diet)Worse genetics
Higher predisposition than average

What this actually is

The two main TCF7L2 variants are rs7903146 and rs12255372.

They are almost always inherited together, which means they act as a single genetic factor.

Their "T" alleles have one of the strongest known links with type 2 diabetes.

Ask your clinician about

  • Resistant Starch
  • Berberine
  • Whey Protein

Named only. Marrow gives no dose and does not recommend these.

From your Hormone Health report

Everything else that came back

The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.

Running above the typical range  (9)
  • FSH — Higher levels
  • SHBG — Higher levels
  • Estradiol (M) — Higher levels
  • Testosterone — Higher levels
  • MTNR1B (Diet & Blood Sugar) — Higher activity
  • DIO1 (Thyroid) — Higher activity
  • DIO2 (Thyroid) — Higher activity
  • GHR — Higher activity
  • MC4R (Weight/ Blood Sugar) — Higher activity
Running below the typical range  (8)
  • DHEAS — Lower levels
  • Luteinizing Hormone (LH) — Lower levels
  • Pregnenolone — Lower levels
  • Prolactin — Lower levels
  • GLP-1 — Lower levels
  • CRHR2 (Stress/HPA Axis) — Lower activity
  • CRHR1 (Stress/HPA Axis) — Lower activity
  • FKBP5 (Stress/ HPA Axis) — Lower activity
In line with most people  (28)
  • Hashimoto's Disease — Typical likelihood, 47th percentile
  • Overactive Thyroid — Typical likelihood, 46th percentile
  • Underactive Thyroid — Typical likelihood, 34th percentile
  • Free T4 — Typical levels
  • T3 (Triiodothyronine) — Typical levels
  • T4 (Thyroxine) — Typical levels
  • TSH — Typical levels
  • Graves' Disease — Typical likelihood
  • Reverse T3 (rT3) — Typical levels
  • Free T3 (fT3) — Typical levels
  • Bioavailable Testosterone — Typical levels
  • DHT — Typical levels
  • Progesterone — Typical levels
  • Insulin — Typical levels
  • Ghrelin — Typical levels
  • IGF-1 — Typical levels
  • Leptin — Typical levels
  • Adiponectin — Typical levels
  • Growth Hormone — Typical levels
  • Cortisol — Typical levels
  • Cushing’s Syndrome — Typical likelihood
  • Addison’s Disease — Typical likelihood
  • HPA Axis — Typical likelihood
  • TPO (Thyroid) — Typical
  • ESR1 (Estrogen) — Typical activity
  • ADIPOQ (Weight/ Blood Sugar) — Typical genetics
  • LEPR (Weight/Leptin Resistance) — Typical activity
  • GIPR (Blood Sugar) — Typical activity

What to do with this

Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.

Methodology

Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.

Limitations

This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.

Performing laboratory & attestation
Performing laboratoryGene by Gene, Ltd.
Laboratory address1445 North Loop West, Suite 760, Houston, TX 77008
CLIA certificationCLIA #45D1102202
CAP accreditationCAP #7212851 · accredited through 7 October 2027
Laboratory DirectorFeng Zhou, PhD, MB(ASCP)
Specimen typeBuccal (cheek) swab — genomic DNA
AccessionMRW-26-6AFD86
Date reported29 July 2026

This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-6AFD86 · © 2026 Marrow Health.