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Genomics · Genetic Reports · Precision Wellness

Kidney Health

Personalized Genetic Report
Chronic Kidney ProblemsAcute Kidney ProblemsKidney Health MarkersKidney Health Genes
Sample ClientReport date: 29 July 2026
Genomics · Genetic Reports · Precision Wellness
Marrow Health Laboratories
Marrow
Accession #: MRW-26-730ACD
Report type: Summary Report
Report status: FINAL

Specimen and client information

Client
Sample Client
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
Accession
MRW-26-730ACD
Panel
Kidney Health
Results scored
22 of 23
Need attention
7
Report
Summary Report

What this report covers

Chronic Kidney Problems · Acute Kidney Problems · Kidney Health Markers · Kidney Health Genes

About this report

This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.

What each result group means

Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.

Your results at a glance

How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 22 results here, 7 came back worth discussing with a clinician and 0 came back in your favour. Bring this document to your appointment.

What this package looks at

Kidney Health — The kidneys play a vital role in filtering waste and maintaining fluid and electrolyte balance in the body. Genetic factors can influence your susceptibility to various kidney-related conditions, ranging from chronic diseases to acute kidney injuries.

What you can actually do

These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.

Changes you can make yourself

1
Avoid Dioxin

Reduce consumption of animal fats, since dioxins accumulate in fat tissue.

Relates to: Kidney Stones, Kidney Failure (ESRD), Renal Colic
relevance
2
Limit Salt Intake

By limiting salt intake, patients with acute kidney injury can help reduce the workload on their kidneys, potentially improving their condition, and managing symptoms like swelling.

Relates to: Kidney Stones, Acute Kidney Injury, Kidney Failure (ESRD), Nephritis
relevance
3
Reduce Oxalate Intake

Avoid high-oxalate foods such as spinach, beets, potatoes, and nuts.

Relates to: Kidney Stones, Acute Kidney Injury, Kidney Failure (ESRD), Nephritis
relevance
4
Limit Protein Intake

Limit your daily protein intake to per kilogram of your body weight.

Relates to: Kidney Stones, Acute Kidney Injury, Kidney Failure (ESRD)
relevance
5
Avoid Sugary Foods & Drinks

Aim to do this daily for ongoing health benefits.

Relates to: Kidney Stones, Kidney Failure (ESRD), Renal Colic
relevance
6
Avoid Secondhand Smoke

Implementing a smoke-free lifestyle involves communicating your needs to family, friends, and coworkers, requesting they respect your choice by smoking away from you.

Relates to: Kidney Stones
relevance
7
Whole-Food Plant-Based Diet

few weeks to avoid digestive discomfort.

Relates to: Kidney Stones, Acute Kidney Injury, Kidney Failure (ESRD), Polycystic Kidney Disease
relevance
8
Pterostilbene

NRPT was safe and well-tolerated, with minor side effects reported in some cases.

Relates to: Acute Kidney Injury
relevance

Worth asking your clinician about

These came up in the research behind your flagged results. They are listed by name so you can ask about them. Marrow is not recommending them, and gives no dose. Supplements interact with prescription medication and with each other — that conversation belongs with your clinician.

1
Omega-3 (Fish Oil)
Relates to: Kidney Stones, Kidney Failure (ESRD), Polycystic Kidney Disease
relevance
2
Hibiscus
Relates to: Kidney Stones
relevance
3
Avoid Vitamin C Supplements
Relates to: Kidney Stones, Polycystic Kidney Disease
relevance
4
N-acetylcysteine (NAC)
Relates to: Kidney Failure (ESRD), Acute Kidney Injury, Nephritis
relevance
5
Magnesium Sulfate
Relates to: Acute Kidney Injury
relevance
6
Potassium Magnesium Citrate
Relates to: Kidney Stones
relevance

Your headline findings

Of the 22 results in this package, these 7 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.

Kidney StonesMore likely
More likey to have kidney stones based on 816,639 genetic variants we looked at
Your risk is greater than 98% of the population and lower than 2% of the population.

What this actually is

Key Takeaways: About 50% of differences in people's chances of developing kidney stones may be due to genetics.

Risk factors include dehydration, excess animal protein, salt, or sugar, obesity, IBD, UTIs, medications, excess vitamin C.

About 11% of American men and 7% of women have kidney stones.

What you can do

  • Avoid Dioxin
    Reduce consumption of animal fats, since dioxins accumulate in fat tissue.
  • Limit Salt Intake
    By limiting salt intake, patients with acute kidney injury can help reduce the workload on their kidneys, potentially improving their condition, and managing symptoms like swelling.
  • Reduce Oxalate Intake
    Avoid high-oxalate foods such as spinach, beets, potatoes, and nuts.
From your Kidney Health report
Renal ColicMore likely
More likely to have a renal colic based on 437,591 genetic variants we looked at
Your risk is greater than 97% of the population and lower than 3% of the population.

What this actually is

Renal colic can be who have a history stones, such as underlying their formation. nonsteroidal necessary.

Hydration is cases, medical stone removal may large to pass or complications.

What you can do

  • Avoid Dioxin
    Reduce consumption of animal fats, since dioxins accumulate in fat tissue.
  • Limit Salt Intake
    By limiting salt intake, patients with acute kidney injury can help reduce the workload on their kidneys, potentially improving their condition, and managing symptoms like swelling.
  • Reduce Oxalate Intake
    Avoid high-oxalate foods such as spinach, beets, potatoes, and nuts.
From your Kidney Health report
Acute Kidney InjuryMore likely
Higher predisposition than 93% of people
Your result sits higher than 93% of the population.

What you can do

  • Pterostilbene
    NRPT was safe and well-tolerated, with minor side effects reported in some cases.
  • Limit Salt Intake
    By limiting salt intake, patients with acute kidney injury can help reduce the workload on their kidneys, potentially improving their condition, and managing symptoms like swelling.

Ask your clinician about

  • Magnesium Sulfate

Named only. Marrow gives no dose and does not recommend these.

From your Kidney Health report
Polycystic Kidney DiseaseMore likely
More likely to have polycystic kidney disease managing symptoms and slowing the based on 30,032 genetic variants we looked at

What you can do

  • Limit Salt Intake
    By limiting salt intake, patients with acute kidney injury can help reduce the workload on their kidneys, potentially improving their condition, and managing symptoms like swelling.

Ask your clinician about

  • Omega-3 (Fish Oil)
  • Avoid Vitamin C Supplements

Named only. Marrow gives no dose and does not recommend these.

From your Kidney Health report
Kidney Failure (ESRD)More likely
Higher predisposition than average

What this actually is

Kidney Failure Conditions that may Diabetes High blood Polycystic Kidney stones Urinary tract Managing these progression of to control blood symptoms.

Dialysis, may be necessary to the blood in cases instances, a kidney solution.

Alongside medical maintaining a staying hydrated, consumption can overall health. essential to adjust outcomes.

What you can do

  • Avoid Dioxin
    Reduce consumption of animal fats, since dioxins accumulate in fat tissue.
  • Avoid Sugary Foods & Drinks
    Aim to do this daily for ongoing health benefits.

Ask your clinician about

  • N-acetylcysteine (NAC)

Named only. Marrow gives no dose and does not recommend these.

From your Kidney Health report
NephritisMore likely
More likely to have nephritis based on 626,851 genetic variants we looked at

What this actually is

Symptoms of nephritis may vary depending on the type and severity of the condition but can include hematuria (blood in the urine), proteinuria (protein in the urine), high blood pressure, and edema (swelling of the body, especially in the legs, ankles, or face).

can arise due to various causes including autoimmune disorders, infections, toxins, or as a reaction to certain medications.

Prompt diagnosis and treatment are crucial in managing the condition to prevent further kidney damage and associated health complications.

What you can do

  • Limit Salt Intake
    By limiting salt intake, patients with acute kidney injury can help reduce the workload on their kidneys, potentially improving their condition, and managing symptoms like swelling.
  • Reduce Oxalate Intake
    Avoid high-oxalate foods such as spinach, beets, potatoes, and nuts.

Ask your clinician about

  • N-acetylcysteine (NAC)

Named only. Marrow gives no dose and does not recommend these.

From your Kidney Health report
Diabetic NephropathyMore likely
More likely to have diabetic nephropathy based on 28,985 genetic variants we looked at

What this actually is

Factors linked to an increased risk of diabetic nephropathy include: Poorly controlled blood sugar levels High blood pressure Long duration of diabetes Smoking Obesity Family history of kidney disease High cholesterol levels Managing diabetic nephropathy involves controlling blood sugar and blood pressure, alongside lifestyle changes.

Common treatments include: Medications: ACE inhibitors or ARBs to control blood pressure, blood sugar-lowering drugs, and statins for cholesterol management.

Dietary changes: Low-protein and low-sodium diets to reduce kidney strain.

From your Kidney Health report

Everything else that came back

The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.

Running above the typical range  (2)
  • Albumin — Higher levels
  • GRHPR (Oxalate & Kidneys) — Higher activity
Running below the typical range  (1)
  • CPS1 (Cardiovascular, Kidney Health) — Lower activity
In line with most people  (12)
  • Kidney Problems — Typical likelihood, 44th percentile
  • Uric Acid — Typical levels, 16th percentile
  • IgA Nephropathy — Typical likelihood
  • Contrast-Induced Nephropathy — Typical likelihood
  • eGFR — Typical levels
  • Creatinine — Typical levels
  • Blood Urea Nitrogen (BUN) — Typical levels
  • Sodium — Typical levels
  • Total Protein — Typical levels
  • Cystatin C — Typical levels
  • Potassium — Typical need
  • Chloride — Typical levels

What to do with this

Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.

Methodology

Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.

Limitations

This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.

Performing laboratory & attestation
Performing laboratoryGene by Gene, Ltd.
Laboratory address1445 North Loop West, Suite 760, Houston, TX 77008
CLIA certificationCLIA #45D1102202
CAP accreditationCAP #7212851 · accredited through 7 October 2027
Laboratory DirectorFeng Zhou, PhD, MB(ASCP)
Specimen typeBuccal (cheek) swab — genomic DNA
AccessionMRW-26-730ACD
Date reported29 July 2026

This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-730ACD · © 2026 Marrow Health.