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Genomics · Genetic Reports · Precision Wellness

Longevity & Healthy Aging

Personalized Genetic Report
Longevity & Healthy AgingConditions Affecting LongevityLongevity MarkersLongevity Genes
Sample ClientReport date: 29 July 2026
Genomics · Genetic Reports · Precision Wellness
Marrow Health Laboratories
Marrow
Accession #: MRW-26-52007B
Report type: Summary Report
Report status: FINAL

Specimen and client information

Client
Sample Client
Specimen type
Buccal (cheek) swab
Date reported
29 July 2026
Accession
MRW-26-52007B
Panel
Longevity & Healthy Aging
Results scored
29 of 33
Need attention
5
Report
Summary Report

What this report covers

Longevity & Healthy Aging · Conditions Affecting Longevity · Longevity Markers · Longevity Genes

About this report

This report reads your DNA and sorts every result into one of five plain-language groups, so you can see at a glance what deserves attention and what does not. Nothing here is a diagnosis. A flagged result means your genetics place you above or below the average person for that trait — a reason to ask a question, not a reason to worry.

What each result group means

Worth a conversation with your doctor
These came back with a higher genetic predisposition than most people. That is not a diagnosis — it means these are the ones worth raising at your next appointment.
Running above the typical range
Your genetics point to these sitting higher than average. Often useful to know, sometimes worth monitoring.
Running below the typical range
Your genetics point to these sitting lower than average. Same idea — context, not alarm.
Working in your favour
Good news. Your genetics look protective or better than average here.
In line with most people
Nothing unusual. These were tested and came back typical — worth having on record.

Your results at a glance

How to read this. A result being flagged does not mean you have a condition — it means your genetics put you above or below the average person for that trait. Of the 29 results here, 5 came back worth discussing with a clinician and 4 came back in your favour. Bring this document to your appointment.

What this package looks at

Longevity & Healthy Aging — Longevity is a fascinating and complex area of study that encompasses not only the length of life but also the quality of life as we age. Genetic factors play a significant role in determining how long we live and how well we age.

What you can actually do

These are ordered by how closely they relate to your flagged results — not generic health advice. Marrow does not prescribe, dose, or tell you to take anything. Diet and lifestyle changes are listed first because they are yours to make. Anything you would swallow is listed separately, by name only, as something to raise with a clinician who knows your history and your medications.

Changes you can make yourself

1
Mediterranean Diet

Limit red meat to a few times a month and include a moderate amount of dairy products.

Relates to: Artery Hardening, Frailty, PPARD (Longevity), Prostate Cancer
relevance
2
Strength Training

Engage in strength training exercises, such as weight lifting or bodyweight exercises, for 60 minutes per session, TA 2 to 3 times per week.

Relates to: Colorectal Cancer, Artery Hardening, PPARD (Longevity), Prostate Cancer
relevance
3
Eat Fiber-Rich Foods

grams per day, spread out over all meals.

Relates to: Colorectal Cancer, Artery Hardening
relevance
4
Avoid Secondhand Smoke

Implementing a smoke-free lifestyle involves communicating your needs to family, friends, and coworkers, requesting they respect your choice by smoking away from you.

Relates to: Artery Hardening, Prostate Cancer
relevance
5
Walking30 minutes

Incorporate at least 30 minutes of brisk walking into your daily routine, aiming for a minimum of five days a week.

Relates to: Artery Hardening, Colorectal Cancer, Frailty
relevance
6
Limit Trans Fats

Avoid fried foods, packaged snacks, baked goods, and fast foods, which are common sources of trans fats.

Relates to: Artery Hardening
relevance
7
Pomegranate Juice

Drink (about 240 milliliters) of 100% pomegranate juice daily, ideally in the morning to incorporate it into your daily routine.

Relates to: Colorectal Cancer, Artery Hardening, Prostate Cancer
relevance
8
Avoid Organochlorine Pesticide Exposure

Consider using air purifiers in homes close to agricultural areas to reduce indoor pesticide levels.

Relates to: Colorectal Cancer, Artery Hardening, Prostate Cancer
relevance

Worth asking your clinician about

These came up in the research behind your flagged results. They are listed by name so you can ask about them. Marrow is not recommending them, and gives no dose. Supplements interact with prescription medication and with each other — that conversation belongs with your clinician.

1
Green Tea
Relates to: Prostate Cancer, Artery Hardening, Colorectal Cancer
relevance
2
Omega-3 (Fish Oil)
Relates to: Artery Hardening, Prostate Cancer
relevance
3
Gotu Kola and Pycnogenol
Relates to: Artery Hardening
relevance
4
Psyllium
Relates to: Artery Hardening
relevance
5
Green Tea Extract
Relates to: Prostate Cancer, Artery Hardening
relevance
6
Maintain Optimal Vitamin D Levels
Relates to: Artery Hardening, Colorectal Cancer, Prostate Cancer, Frailty
relevance

Your headline findings

Of the 29 results in this package, these 5 came back furthest from the population average. Each one below explains what it is, where you sit, and which report it came from. Start here.

Artery HardeningMore likely
More likely to have atherosclerosis based on 51,588 genetic variants we looked at
Your risk is greater than 95% of the population and lower than 5% of the population.

What this actually is

Key Takeaways: About 60% of differences in people's chances of having atherosclerosis may be due to genetics Risk factors: being male, high blood pressure and cholesterol, diabetes, obesity, smoking, lack of exercise, poor diet, and age.

Artery hardening begins at a young age and your genetics, lifestyle, diet, and exercise may all impact how much and how fast it develops over the course of your lifetime.

The arteries are blood vessels that carry oxygen and nutrients from the heart to the rest of the body.

What you can do

  • Mediterranean Diet
    Limit red meat to a few times a month and include a moderate amount of dairy products.
  • Strength Training
    Engage in strength training exercises, such as weight lifting or bodyweight exercises, for 60 minutes per session, TA 2 to 3 times per week.
  • Eat Fiber-Rich Foods
    grams per day, spread out over all meals.
From your Longevity & Healthy Aging report
Prostate CancerMore likely
More likely to get prostate cancer based on 1,049,413 genetic variants we looked at
Your risk is greater than 94% of the population and lower than 6% of the population.

What this actually is

The exact cause of prostate cancer is not clearly understood, but several factors have been identified that increase the risk of developing this disease: Age: The risk increases significantly after age 50, and it is most common in men over 65.

Family history: Having a father or brother with prostate cancer more than doubles a man’s risk.

Race/Ethnicity: African-American men have a higher risk of prostate cancer than men of other races.

What you can do

  • Mediterranean Diet
    Limit red meat to a few times a month and include a moderate amount of dairy products.

Ask your clinician about

  • Green Tea
  • Green Tea Extract

Named only. Marrow gives no dose and does not recommend these.

From your Longevity & Healthy Aging report
FrailtyMore likely
More likely to experience frailty based on 16,767 genetic variants we looked at
Your risk is greater than 89% of the population and lower than 11% of the population.

What this actually is

The clinical presentation of frailty includes symptoms such as fatigue, muscle weakness, slowed performance, and diminished energy reserves.

Due to its multidimensional nature, the diagnosis of frailty involves a comprehensive assessment of physical capability, nutritional status, and social and psychological functions.

Management strategies for frailty are typically multidisciplinary and can include tailored exercise programs to improve physical function, nutritional interventions to address potential deficiencies or undernutrition, and supportive measures to enhance social support and cognitive stimulation.

What you can do

  • Mediterranean Diet
    Limit red meat to a few times a month and include a moderate amount of dairy products.
  • Strength Training
    Engage in strength training exercises, such as weight lifting or bodyweight exercises, for 60 minutes per session, TA 2 to 3 times per week.

Ask your clinician about

  • Maintain Optimal Vitamin D Levels

Named only. Marrow gives no dose and does not recommend these.

From your Longevity & Healthy Aging report
Colorectal CancerMore likely
More likely to get colorectal cancer based on 1,049,410 genetic variants we looked at
Your risk is greater than 73% of the population and lower than 27% of the population.

What this actually is

While the exact cause of colorectal cancer is not fully understood, several factors increase the risk of developing this disease: Age: The majority of cases occur in people aged 50 and older, though incidence rates are rising among younger populations.

Family history: Having a family history of colorectal cancer or polyps increases one's risk.

Personal history: Those with a history of inflammatory bowel disease (like Crohn's disease or ulcerative colitis), or who have had colorectal cancer or adenomatous polyps before are at higher risk.

What you can do

  • Strength Training
    Engage in strength training exercises, such as weight lifting or bodyweight exercises, for 60 minutes per session, TA 2 to 3 times per week.
  • Eat Fiber-Rich Foods
    grams per day, spread out over all meals.
  • Pomegranate Juice
    Drink (about 240 milliliters) of 100% pomegranate juice daily, ideally in the morning to incorporate it into your daily routine.
From your Longevity & Healthy Aging report
PPARD (Longevity)Worse
Higher predisposition than average

What this actually is

The rs2016520 was found to be exceptionally long Chinese people genotype is more above.

However, this Moreover, cholesterol and subjects.

For example, as using fats as the carbohydrates.

What you can do

  • Mediterranean Diet
    Limit red meat to a few times a month and include a moderate amount of dairy products.
  • Strength Training
    Engage in strength training exercises, such as weight lifting or bodyweight exercises, for 60 minutes per session, TA 2 to 3 times per week.
From your Longevity & Healthy Aging report

Where your genetics are working for you

Not everything in a genetic report is a warning. These came back protective or better than average.

Cognitive DeclineLess likely
Less likely to have cognitive decline based on 272,168 genetic variants we looked at
Your risk is greater than 1% of the population and lower than 99% of the population.

What this actually is

Mild cognitive decline is a normal part of aging that can affect cognitive functions such as memory, attention, and problem-solving.

About 60-70% of the differences in people’s cognitive decline may come from genetics.

For example, genetically high total and bioavailable testosterone may be causally associated with larger gray matter volume in men [R, R, R].

From your Longevity & Healthy Aging report
Muscle LossLess likely
Less likely to have sarcopenia based on 10 genetic variants we looked at

What this actually is

About 60% of the differences in sarcopenia may be due to genetics.

Some genes associated with muscle growth, repair, and inflammation have been linked to sarcopenia susceptibility.

For example, genetically higher IGF-1 levels may be causally associated with higher muscle mass and a lower risk of muscle loss [R, R].

From your Longevity & Healthy Aging report
Lung CancerLess likely
Less likely to have lung cancer based on 849,819 genetic variants we looked at

What this actually is

Exposure to cigarette smoke is by far the main risk factor for lung cancer.

Other factors that may increase the risk include: Exposure to asbestos and other substances Exposure to radon Previous radiation therapy to the chest Family history Treatment for lung cancer usually begins with surgery to remove the tumor.

Treatment might start with chemotherapy and radiation instead depending on factors such as overall health, cancer type and stage, and preferences of the patient.

From your Longevity & Healthy Aging report

Everything else that came back

The remaining results, grouped by what they mean. Every one of these is explained in full — with the genes and variants behind it — in the technical version of this report.

Running above the typical range  (1)
  • CFH (Eye Health/ Longevity) — Higher activity
Running below the typical range  (2)
  • ADA (Cognition/Longevity) — Lower activity
  • CETP (Cholesterol/ Longevity) — Lower activity
Working in your favour  (1)
  • IGF1R (Longevity) — Better
In line with most people  (17)
  • Aging Eyes — Typical likelihood, 77th percentile
  • Alzheimer's Disease — Typical likelihood, 65th percentile
  • Cardiovascular Disease — Typical likelihood, 60th percentile
  • Age-Related Macular Degeneration — Typical likelihood, 44th percentile
  • Facial Wrinkles — Typical
  • Longevity — Typical
  • Healthy Aging — Typical
  • Hair Graying — Typical
  • Pancreatic Cancer — Typical likelihood
  • SIRT1 (Longevity) — Typical activity
  • TERT (Longevity) — Typical activity
  • OBFC1 (Longevity) — Typical activity
  • AKT1 (Longevity) — Typical genetics
  • APOC3 (Blood Lipids/ Longevity) — Typical activity
  • FOXO3 (Longevity) — Typical activity
  • TAS2R16 (Bitter Taste/ Longevity) — Typical activity
  • PARP1 (Longevity, Cognition) — Typical genetics

What to do with this

Genetics is a predisposition, not a verdict. The single most useful thing you can do with this document is take it to a clinician and talk through the flagged findings — especially any that line up with symptoms you already have or conditions that run in your family. Nothing here changes: your DNA is the same at 60 as it is today, so this report does not expire.

Methodology

Genotyping was performed on DNA extracted from a buccal (cheek) swab using a genome-wide array. Results are derived from peer-reviewed genome-wide association data and, where applicable, published clinical guidelines. Each report was scored independently against its own reference set. Percentile figures describe where your result sits relative to a reference population.

Limitations

This is a laboratory-developed test. It has not been cleared or approved by the U.S. Food and Drug Administration. Genotyping does not detect all variants in the genes assessed; the absence of a flagged result does not exclude risk. Predisposition is probabilistic and is modified by environment, lifestyle, ancestry and family history. Results must be interpreted by a qualified healthcare professional and must not be used alone to diagnose, treat, or alter any medication regimen. Marrow does not recommend, prescribe, or dose any supplement or medication.

Performing laboratory & attestation
Performing laboratoryGene by Gene, Ltd.
Laboratory address1445 North Loop West, Suite 760, Houston, TX 77008
CLIA certificationCLIA #45D1102202
CAP accreditationCAP #7212851 · accredited through 7 October 2027
Laboratory DirectorFeng Zhou, PhD, MB(ASCP)
Specimen typeBuccal (cheek) swab — genomic DNA
AccessionMRW-26-52007B
Date reported29 July 2026

This specimen was tested at Gene by Gene, Ltd., 1445 North Loop West, Suite 760, Houston, TX 77008, under CLIA #45D1102202 and CAP #7212851. Laboratory Director: Feng Zhou, PhD, MB(ASCP). Marrow Health is not a clinical laboratory and does not perform testing; Marrow prepares and delivers this report from data produced by the performing laboratory named above. Report generated 29 July 2026 · Accession MRW-26-52007B · © 2026 Marrow Health.